Miwa Haruo, Sugimori Kazuya, Irie Kuniyasu, Goda Yoshihiro, Shibasaki Kozue, Ishino Yugo, Tsunoda Shotaro, Endo Kazuki, Oishi Ritsuko, Suzuki Yuichi, Tsuchiya Hiromi, Funaoka Akihiro, Anan Hideyuki, Suzuki Yoshimasa, Kaneko Takashi, Morimoto Manabu, Numata Kazushi, Maeda Shin
Gastroenterological Center Yokohama City University Medical Center Yokohama Japan.
Department of Gastroenterology Yokohama City University Hospital Yokohama Japan.
DEN Open. 2025 Jun 2;6(1):e70152. doi: 10.1002/deo2.70152. eCollection 2026 Apr.
To evaluate the clinical outcomes of peroral cholangiopancreatoscopy (POCPS) using the 9-Fr eyeMAX for the diagnosis of pancreatobiliary diseases.
This retrospective study enrolled 43 patients who underwent POCPS using the 9-Fr eyeMAX for diagnostic procedures at two tertiary referral centers between May 2023 and November 2024. The primary outcome was the incidence of adverse events following POCPS. Patient backgrounds, procedural details, technical success (successful insertion of the 9-Fr eyeMAX), and adequate tissue sampling were also analyzed.
Of the 43 patients, 32 were male, and 11 were female, with a median age of 75 years (range, 46-87 years). Peroral cholangioscopy (POCS) was performed on 30 patients. The final diagnosis in this cohort was an ampullary tumor ( = 2), extrahepatic bile duct cancer ( = 16), gallbladder cancer ( = 3), metastatic liver tumor ( = 1), and benign biliary stricture ( = 8). The adequate tissue sampling rate for the POCS was 86.4%. Adverse events after POCS occurred in two patients (6.7%), including mild pancreatitis ( = 1) and fever ( = 1). Peroral pancreatoscopy (POPS) was performed on 13 patients. The final diagnoses of all patients undergoing POPS were intraductal papillary mucinous neoplasms (IPMN), categorized as branch duct-type IPMN ( = 1), mixed-type IPMN ( = 8), and main duct-type IPMN ( = 4). The technical success rate was 92.3% (12/13). The tissue sampling rate for POPS was 83.6%. No adverse events, such as pancreatitis, were observed.
The 9-Fr eyeMAX facilitates a safe POCPS procedure, achieving a high technical success rate and an adequate tissue sampling rate.
评估使用9F eyeMAX经口胆管胰管镜检查（POCPS）诊断胰胆疾病的临床结果。
这项回顾性研究纳入了43例患者，他们于2023年5月至2024年11月在两家三级转诊中心接受了使用9F eyeMAX进行诊断程序的POCPS。主要结果是POCPS后不良事件的发生率。还分析了患者背景、手术细节、技术成功率（9F eyeMAX成功插入）和足够的组织采样情况。
43例患者中，男性32例，女性11例，中位年龄75岁（范围46 - 87岁）。30例患者进行了经口胆管镜检查（POCS）。该队列的最终诊断为壶腹肿瘤（n = 2）、肝外胆管癌（n = 16）、胆囊癌（n = 3）、肝转移瘤（n = 1）和良性胆管狭窄（n = 8）。POCS的足够组织采样率为86.4%。POCS后不良事件发生在2例患者（6.7%）中，包括轻度胰腺炎（n = 1）和发热（n = 1）。13例患者进行了经口胰管镜检查（POPS）。所有接受POPS患者的最终诊断均为导管内乳头状黏液性肿瘤（IPMN），分为分支导管型IPMN（n = 1）、混合型IPMN（n = 8）和主胰管型IPMN（n = 4）。技术成功率为92.3%（12/13）。POPS的组织采样率为83.6%。未观察到胰腺炎等不良事件。
9F eyeMAX有助于安全进行POCPS手术，实现了较高的技术成功率和足够的组织采样率。
