Hulmes D J, Holmes D F, Cummings C
J Mol Biol. 1985 Aug 5;184(3):473-7. doi: 10.1016/0022-2836(85)90295-5.
A new image processing technique, content-dependent anisotropic spatial frequency filtering, has been developed to visualize the location and orientation of crystalline regions in collagen fibril cross-sections. The results show that most crystalline regions are oriented with their approximately 4 nm periodicity directed radially from the fibril centre. This periodicity corresponds to the separation between rows of molecular ends in the quasi-hexagonal molecular packing scheme. The extent of crystallinity increases with radius and frequently the lattice is either continuously distorted or interrupted by sharp discontinuities.
一种新的图像处理技术，即基于内容的各向异性空间频率滤波，已被开发出来用于可视化胶原纤维横截面中结晶区域的位置和取向。结果表明，大多数结晶区域的取向是其约4纳米的周期性从纤维中心径向指向。这种周期性对应于准六边形分子堆积方案中分子末端排之间的间距。结晶度随着半径的增加而增加，并且晶格经常要么连续扭曲，要么被尖锐的不连续性打断。
