别怪罪于酒精！酒精与创伤结局：一项为期10年的单中心回顾性研究。

Don't blame it on the alcohol! Alcohol and Trauma Outcomes: A 10 year retrospective single-center study.

作者信息

Nowacki Joseph C, Jones Eli, Armento Isabella, Hunter Krystal, Slotman Justin, Goldenberg-Sandau Anna

机构信息

Cooper Medical School of Rowan University, Camden, NJ, USA.

Division of Trauma, Cooper University Hospital, Camden, NJ, USA.

出版信息

Am J Surg. 2025 Oct;248:116444. doi: 10.1016/j.amjsurg.2025.116444. Epub 2025 May 23.

DOI:10.1016/j.amjsurg.2025.116444

PMID:40460586

Abstract

BACKGROUND

Alcohol use is associated with injury. Although ACS guidelines require screening injured patients for alcohol misuse, outcome data remains inconclusive.

METHODS

This single-center, 10-year (2013-2023) retrospective study examined patients with ISS >15 at a Level I trauma center. Patients from an institutional registry were grouped by blood alcohol content (BAC): positive (>80 mg/dL, BAC-P) or negative (BAC-N).

RESULTS

Of 517 patients, 401 were BAC-N and 116 BAC-P. BAC-P patients were younger, mostly male, with lower GCS, higher ISS, and higher Shock Indexes (p < 0.001). They required emergency surgery more often (p = 0.023), ICU care (p < 0.001), and had longer hospital stays (12.1 vs. 8.9 days, p = 0.003). Mortality rates were similar between groups. BAC-P patients received more aggressive interventions, possibly mitigating alcohol-related harm.

CONCLUSION

Though BAC-P trauma patients had more severe injuries and required more aggressive care, the lack of difference in mortality suggests that targeted, evidence-based management strategies may benefit intoxicated trauma patients.

摘要

背景

饮酒与损伤有关。尽管美国外科医师学会（ACS）指南要求对受伤患者进行酒精滥用筛查，但结果数据仍无定论。

方法

这项单中心、为期10年（2013 - 2023年）的回顾性研究，对一家一级创伤中心中损伤严重程度评分（ISS）>15的患者进行了检查。来自机构登记处的患者按血液酒精含量（BAC）分组：阳性（>80mg/dL，BAC-P）或阴性（BAC-N）。

结果

在517例患者中，401例为BAC-N，116例为BAC-P。BAC-P组患者更年轻，多为男性，格拉斯哥昏迷评分（GCS）更低，ISS更高，休克指数更高（p<0.001）。他们更常需要急诊手术（p = 0.023）、重症监护病房（ICU）护理（p<0.001），住院时间更长（12.1天对8.9天，p = 0.003）。两组之间的死亡率相似。BAC-P组患者接受了更积极的干预，可能减轻了与酒精相关的伤害。