Shemesh Sharon, Haviv Ruby, Uziel Yosef
Pediatric Rheumatology Unit, Pediatric Department, Meir Medical Center, Kfar Saba, Israel and Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Curr Opin Rheumatol. 2025 Sep 1;37(5):289-295. doi: 10.1097/BOR.0000000000001101. Epub 2025 Jun 4.
This review provides a comprehensive perspective on poststreptococcal rheumatic manifestations in pediatric patients by integrating recent updates and a literature review, with particular focus on poststreptococcal reactive arthritis and acute rheumatic fever.
Poststreptococcal reactive arthritis presents with a unique clinical profile, distinguishing it from other poststreptococcal conditions in pediatric patients, especially acute rheumatic fever. Recent updates underscore the importance of diligent monitoring and management to mitigate potential cardiac complications, despite the relatively low incidence of carditis following poststreptococcal reactive arthritis.
The diagnosis of poststreptococcal reactive arthritis is often challenging due to significant overlap with other poststreptococcal syndromes, particularly acute rheumatic fever. Given the potential for cardiac complications in acute rheumatic fever, accurate differentiation between the two conditions is imperative. Ongoing research continues to refine diagnostic criteria and treatment approaches, emphasizing the need for clinicians to remain vigilant in recognizing and differentiating between the two syndromes.
本综述通过整合近期进展和文献回顾，全面阐述儿科患者链球菌感染后风湿性表现，特别关注链球菌感染后反应性关节炎和急性风湿热。
链球菌感染后反应性关节炎具有独特的临床特征，使其与儿科患者的其他链球菌感染后病症，尤其是急性风湿热相区别。近期进展强调了尽管链球菌感染后反应性关节炎后发生心脏炎的发生率相对较低，但仍需进行密切监测和管理以减轻潜在的心脏并发症。
由于与其他链球菌感染后综合征，尤其是急性风湿热存在显著重叠，链球菌感染后反应性关节炎的诊断往往具有挑战性。鉴于急性风湿热存在心脏并发症的可能性，准确区分这两种病症至关重要。正在进行的研究不断完善诊断标准和治疗方法，强调临床医生需要保持警惕，以识别和区分这两种综合征。
