Singh Vishal, Dabas A K, Singh Pulkit, Dogra Pavitra Manu, Singhal Gaurav
Head of Department & Senior Advisor (Medicine & Nephrology), Army Hospital (R&R), Delhi Cantt, India.
Head of Department & Senior Advisor (Surgery & Vascular Surgery), Army Hospital (R&R), Delhi Cantt, India.
Med J Armed Forces India. 2025 May-Jun;81(3):351-355. doi: 10.1016/j.mjafi.2023.04.011. Epub 2023 Jun 4.
Infections, both traditional and opportunistic, constitute a major cause of morbidity and mortality in kidney transplant recipients. Mucorales, ubiquitous environmental fungi, is the cause for a rare but devastating opportunistic infection. Here, we describe a patient with an unusual mucor infection involving the graft kidney and the graft renal artery who, following a deceased donor kidney transplantation, presented in the early posttransplantation period with a vascular blowout and massive hemorrhage. Prompt aggressive resuscitation and surgical intervention saved his life; however, the renal allograft could not be preserved. The key to success in such a life-threatening atypical presentation includes a high index of suspicion, early recognition, and prompt therapeutic intervention.
感染,包括传统感染和机会性感染,是肾移植受者发病和死亡的主要原因。毛霉目真菌是普遍存在于环境中的真菌,是一种罕见但具有毁灭性的机会性感染的病因。在此,我们描述了一名肾移植受者,在接受尸体供肾移植后,移植肾和移植肾动脉发生了罕见的毛霉感染,在移植术后早期出现血管破裂和大量出血。迅速积极的复苏和手术干预挽救了他的生命;然而,移植肾未能保住。对于这种危及生命的非典型表现,成功的关键包括高度的怀疑指数、早期识别和及时的治疗干预。