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单次大剂量两性霉素B治疗新型隐球菌性脑膜炎：印度的首次经验。

Single high-dose amphotericin B for cryptococcal meningitis: First Indian experience.

作者信息

Vashisht Rohit, Arora Sumit, Kumar Abhinav, Patel Ankita, Saxena Surbhi, Rohan Akhil, Narayan Ashok

机构信息

Associate Professor, Department of Internal Medicine, Armed Forces Medical College, Pune, India.

Associate Professor (Medicine), Army College of Medical Sciences, Delhi Cantt, India.

出版信息

Med J Armed Forces India. 2025 May-Jun;81(3):361-365. doi: 10.1016/j.mjafi.2023.08.001. Epub 2023 Oct 11.

DOI:10.1016/j.mjafi.2023.08.001
PMID:40463615
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12127267/
Abstract

Cryptococcus is a common organism causing central nervous system disease in people living with HIV (PLHIV). The treatment of this infection entails a costly regimen of Amphotericin. World Health Organization (WHO) recently recommended a cost-effective single high-dose regimen with liposomal amphotericin B for the treatment of cryptococcal meningitis. We hereby present an Indian experience with this regimen in two patients managed at immunodeficiency centers of the Armed Forces.

摘要

隐球菌是导致艾滋病病毒感染者（PLHIV）中枢神经系统疾病的常见病原体。这种感染的治疗需要使用昂贵的两性霉素治疗方案。世界卫生组织（WHO）最近推荐了一种具有成本效益的高剂量单药疗法，即使用脂质体两性霉素B治疗隐球菌性脑膜炎。在此，我们介绍在武装部队免疫缺陷中心接受治疗的两名患者使用该疗法的印度经验。

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本文引用的文献

1
Cost-effectiveness of single, high-dose, liposomal amphotericin regimen for HIV-associated cryptococcal meningitis in five countries in sub-Saharan Africa: an economic analysis of the AMBITION-cm trial.
Lancet Glob Health. 2022 Dec;10(12):e1845-e1854. doi: 10.1016/S2214-109X(22)00450-8.
2
Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis.
N Engl J Med. 2022 Mar 24;386(12):1109-1120. doi: 10.1056/NEJMoa2111904.
3
Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy.
Nat Rev Neurol. 2017 Jan;13(1):13-24. doi: 10.1038/nrneurol.2016.167. Epub 2016 Nov 25.
4
Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis.
Clin Infect Dis. 2011 Nov;53(10):1019-23. doi: 10.1093/cid/cir613. Epub 2011 Sep 21.
5
Adult meningitis in a setting of high HIV and TB prevalence: findings from 4961 suspected cases.
BMC Infect Dis. 2010 Mar 15;10:67. doi: 10.1186/1471-2334-10-67.

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