Strobel S, Ferguson A
Klin Padiatr. 1985 Jul-Aug;197(4):297-301. doi: 10.1055/s-2008-1033987.
When the first encounter with an antigen is by the oral route several different immune responses can occur. The spectrum of effects on systemic immunity ranges from immunological hyporesponsiveness (oral tolerance) to active sensitisation (priming). In this paper, the immunological principles underlying these effects are discussed and circumstances which influence them are demonstrated, particular emphasis being placed on experimental work in adult and neonatal mice.
当首次通过口服途径接触抗原时，可能会发生几种不同的免疫反应。对全身免疫的影响范围从免疫低反应性（口服耐受）到主动致敏（启动）。本文讨论了这些效应背后的免疫学原理，并展示了影响它们的情况，特别强调了在成年和新生小鼠身上进行的实验工作。
