Jiang Yanan, Jiang Yerong, Gao Yu, Yan Lu, Zhao Demei
Department of Burns and Plastic Surgery, The Affiliated Hospital of Nanjing University Medical School, Nanjing Drum Tower Hospital, Nanjing, People's Republic of China.
Medical Cosmetic Center, The Affiliated Hospital of Nanjing University Medical School, Nanjing Drum Tower Hospital, Nanjing, People's Republic of China.
Aesthetic Plast Surg. 2025 Jun 4. doi: 10.1007/s00266-025-04903-y.
The harmonization of micro-droplet botulinum toxin injections with either micro-crosslinked sodium hyaluronate gel or focused ultrasound technology necessitating a comprehensive evaluation of their differential impact.
A retrospective analysis of clinical data was conducted on 114 patients who underwent facial rejuvenation treatment. The patients were divided into two groups: one receiving botulinum toxin micro-droplet injection combined with micro-crosslinked hyaluronic acid sodium gel (n=56) and the other receiving botulinum toxin micro-droplet injection combined with focused ultrasound technology (n=58). The study assessed baseline characteristics, procedural aspects, recovery, side effects, facial laxity and rejuvenation (FLR), and quality of life using validated rating scales and criteria.
The study revealed several significant findings. The procedural duration was shorter in the micro-crosslinked sodium hyaluronate gel group, whereas the time to return to normal activities was shorter in the focused ultrasound group. The incidence of edema and erythema was significantly lower in the focused ultrasound group. FLR scale scores showed better skin elasticity and tightness in the focused ultrasound group, while quality of life scores indicated variations in emotion management and return to social function between the two groups.
The study emphasizes the multifaceted impact of botulinum toxin micro-droplet injection combined with micro-crosslinked sodium hyaluronate gel and focused ultrasound technology on various parameters in facial rejuvenation treatment. These findings provide valuable insights into the differential effects of these treatment modalities, highlighting the need for personalized approaches and patient-centered care in cosmetic dermatology and plastic surgery.
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将微滴肉毒杆菌毒素注射与微交联透明质酸钠凝胶或聚焦超声技术相结合，需要对它们的不同影响进行全面评估。
对114例接受面部年轻化治疗的患者的临床资料进行回顾性分析。患者分为两组：一组接受肉毒杆菌毒素微滴注射联合微交联透明质酸钠凝胶（n = 56），另一组接受肉毒杆菌毒素微滴注射联合聚焦超声技术（n = 58）。该研究使用经过验证的评分量表和标准评估了基线特征、手术过程、恢复情况、副作用、面部松弛和年轻化（FLR）以及生活质量。
该研究揭示了几个重要发现。微交联透明质酸钠凝胶组的手术持续时间较短，而聚焦超声组恢复正常活动的时间较短。聚焦超声组水肿和红斑的发生率显著较低。FLR量表评分显示聚焦超声组的皮肤弹性和紧致度更好，而生活质量评分表明两组在情绪管理和恢复社交功能方面存在差异。
该研究强调了肉毒杆菌毒素微滴注射联合微交联透明质酸钠凝胶和聚焦超声技术对面部年轻化治疗中各种参数的多方面影响。这些发现为这些治疗方式的不同效果提供了有价值的见解，突出了在美容皮肤科和整形外科中采用个性化方法和以患者为中心的护理的必要性。
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