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巴西妊娠梅毒和先天性梅毒指标的时间分析:能否在2030年前消除垂直传播?

Temporal analysis of gestational and congenital syphilis indicators in Brazil: toward the elimination of vertical transmission by 2030?

作者信息

Pavinati Gabriel, Lima Lucas Vinícius de, Stolarz Marjorie Fairuzy, Gomes Melissa Ferrari, Turquino Sidnei Nathan Soares, Magnabosco Gabriela Tavares

机构信息

Universidade Estadual de Maringá, Graduate Program in Nursing - Maringá (PR), Brazil.

出版信息

Rev Bras Epidemiol. 2025 Jun 2;28:e250028. doi: 10.1590/1980-549720250028. eCollection 2025.

Abstract

OBJECTIVE

To analyze, at national and regional levels, the trend of proxy indicators for the progress toward the elimination of the vertical transmission of syphilis in Brazil.

METHODS

This is an ecological study that assessed the annual percent change (APC) of indicators related to gestational and congenital syphilis.

RESULTS

An APC of 11.15% was observed in the detection rate of gestational syphilis (95% confidence interval - 95%CI 2.78-23.19), with stability in congenital syphilis across all regions. There was a reduction of prenatal care coverage among pregnant women with syphilis (APC=-7.34%; 95%CI -10.15; -5.33), and also a decrease in late diagnosis of the infection (APC=-10.77%; 95%CI -14.29; -8.79).

CONCLUSIONS

We evidenced challenges in achieving the 2030 elimination targets, highlighting the need for adjustments in current public policies on syphilis prevention and control.

摘要

目的

在国家和地区层面分析巴西消除梅毒垂直传播进程的替代指标趋势。

方法

这是一项生态研究,评估了与妊娠梅毒和先天性梅毒相关指标的年度变化百分比(APC)。

结果

妊娠梅毒检测率的年度变化百分比为11.15%(95%置信区间-95%CI 2.78-23.19),所有地区先天性梅毒情况稳定。梅毒孕妇的产前保健覆盖率有所下降(年度变化百分比=-7.34%;95%CI -10.15;-5.33),感染的晚期诊断率也有所下降(年度变化百分比=-10.77%;95%CI -14.29;-8.79)。

结论

我们证明了在实现2030年消除目标方面存在挑战,强调需要调整当前梅毒预防和控制的公共政策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/851e/12129237/8cb9fb0aea45/1980-5497-rbepid-28-e250028-gf01.jpg

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