Heichel Theres, Kersten Jan F, Braumann Antje, Krambeck Kathrin, Bonness Sonja, Schröder-Kraft Claudia, Ofenloch Robert, Weisshaar Elke, Strom Kerstin, Skudlik Christoph, Sonsmann Flora, Wilke Annika, Nienhaus Albert, John Swen Malte, Brans Richard
Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) at the Osnabrück University, Osnabrück, Germany.
Department of Dermatology, Environmental Medicine and Health Theory, Osnabrück University, Osnabrück, Germany.
Contact Dermatitis. 2025 Oct;93(4):305-315. doi: 10.1111/cod.14822. Epub 2025 Jun 4.
Glove liners (GLs) are worn under impermeable gloves to prevent occlusion effects.
To evaluate the acceptance and tolerability of cotton gloves (COT) and semipermeable Sympatex gloves (SYM) as GLs in patients with hand dermatoses.
In a prospective multicenter study, 210 patients with work-related hand dermatoses were invited to wear either COT or SYM as GLs for 4 weeks underneath occlusive protective gloves during their regular work tasks. Acceptance of GL and health-related quality of life (HRQoL) were assessed by questionnaires and the disease severity by the Osnabrueck Hand Eczema Severity Index.
A total of 178 data sets were available (SYM: n = 89/103, 86.4%; COT: n = 89/107, 83.2%). Both GLs did not impair work performance and were applicable in various work activities. SYM received better ratings regarding climate conditions, mobility and tactility. COT showed superiority in fit, donning and doffing. No substantial intergroup differences regarding disease severity and HRQoL were observed.
SYM and COT were well tolerated and accepted, suggesting that SYM is a reasonable alternative for COT as GL in patients with hand dermatoses. The choice of material of GLs may depend on occupation-specific requirements for the performed tasks, individual needs and preferences.
手套内衬（GLs）戴在不透气手套内以防止闭塞效应。
评估棉质手套（COT）和半透性Sympatex手套（SYM）作为手部皮肤病患者的手套内衬的可接受性和耐受性。
在一项前瞻性多中心研究中，邀请210名患有与工作相关手部皮肤病的患者在日常工作任务期间，在闭塞性防护手套下佩戴COT或SYM作为手套内衬4周。通过问卷调查评估对手套内衬的接受程度和与健康相关的生活质量（HRQoL），并通过奥斯纳布吕克手部湿疹严重程度指数评估疾病严重程度。
共获得178个数据集（SYM：n = 89/103，86.4%；COT：n = 89/107，83.2%）。两种手套内衬均未影响工作表现，且适用于各种工作活动。SYM在气候条件、灵活性和触感方面获得了更好的评分。COT在贴合度、穿戴和脱卸方面表现更优。在疾病严重程度和HRQoL方面未观察到显著的组间差异。
SYM和COT耐受性良好且被接受，这表明SYM作为手部皮肤病患者的手套内衬是COT的合理替代品。手套内衬材料的选择可能取决于所执行任务的特定职业要求、个人需求和偏好。
