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童年创伤对产后抑郁症的影响:一项前瞻性队列研究。

The influence of childhood trauma on postpartum depression: A prospective cohort study.

作者信息

Camargo Júnior Elton Brás, Alves Leticia Furtado, Andrade Ana Carolina, Marrara Julio Ruiz, Fernandes Maria Neyrian de Fátima, Hu Jie, Gherardi-Donato Edilaine Cristina da Silva

机构信息

University of Rio Verde, Fazenda Fontes do Saber, Campus Universitário, Rio Verde, Goiás, Brazil.

University of Rio Verde, Fazenda Fontes do Saber, Campus Universitário, Rio Verde, Goiás, Brazil.

出版信息

Arch Psychiatr Nurs. 2025 Jun;56:151892. doi: 10.1016/j.apnu.2025.151892. Epub 2025 May 27.

DOI:10.1016/j.apnu.2025.151892
PMID:40467289
Abstract

PURPOSE

This study aimed to analyze the influence of childhood trauma on postpartum depression (PPD) through a prospective longitudinal evaluation.

METHODS

A prospective cohort study was conducted with women evaluated at two postpartum periods: the immediate postpartum period and between the middle and end of the third month. Data were collected using the Childhood Trauma Questionnaire (CTQ) which assesses five types of trauma (emotional abuse, physical abuse, sexual abuse, emotional neglect, and physical neglect), and the Edinburgh Postnatal Depression Scale (EPDS). Generalized Estimating Equations (GEE) and adjusted multinomial logistic regressions were performed.

RESULTS

This study included 153 women who completed both assessments. The type of childhood trauma evaluated significantly influenced PPD symptoms at both time points. The PPD symptoms remained stable over time, with no significant interaction between trauma exposure and time. Emotional abuse, physical abuse, sexual abuse, emotional neglect, and physical neglect were found to be significant predictors of chronic PPD. Emotional abuse, physical abuse, and emotional neglect are also associated with early onset PPD. For late-onset PPD, only emotional neglect and sexual abuse remained as significant predictors. Emotional abuse was the most influential predictor of both early-onset and chronic PPD, while emotional neglect had the greatest impact on late-onset PPD.

CONCLUSION

This study highlighted the significant influence of childhood trauma on PPD. Furthermore, PPD symptoms remained stable over time. Early screening for PPD in postpartum women and the identification of childhood trauma during pregnancy are essential to mitigate PPD risk factors.

摘要

目的

本研究旨在通过前瞻性纵向评估分析童年创伤对产后抑郁症(PPD)的影响。

方法

对女性进行前瞻性队列研究,在两个产后阶段进行评估:产后即刻以及第三个月中旬至月末。使用童年创伤问卷(CTQ)收集数据,该问卷评估五种类型的创伤(情感虐待、身体虐待、性虐待、情感忽视和身体忽视),以及爱丁堡产后抑郁量表(EPDS)。进行广义估计方程(GEE)和调整后的多项逻辑回归分析。

结果

本研究纳入了153名完成两项评估的女性。所评估的童年创伤类型在两个时间点均对PPD症状有显著影响。PPD症状随时间保持稳定,创伤暴露与时间之间无显著交互作用。情感虐待、身体虐待、性虐待、情感忽视和身体忽视被发现是慢性PPD的显著预测因素。情感虐待、身体虐待和情感忽视也与早发型PPD相关。对于晚发型PPD,只有情感忽视和性虐待仍然是显著预测因素。情感虐待是早发型和慢性PPD最具影响力的预测因素,而情感忽视对晚发型PPD影响最大。

结论

本研究强调了童年创伤对PPD的显著影响。此外,PPD症状随时间保持稳定。对产后女性进行PPD早期筛查以及在孕期识别童年创伤对于减轻PPD风险因素至关重要。

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