Zhou Suting, Yu Meimei, Wang Yumeng, Zhang Yuxia, Wang Xiangya, Ran Fen
Energy Storage Institute of Lanzhou University of Technology, School of Materials Science and Engineering, State Key Laboratory of Advanced Processing and Recycling of Non-ferrous Metals, Lanzhou University of Technology, Lanzhou 730050, China.
Biomacromolecules. 2025 Jul 14;26(7):4297-4307. doi: 10.1021/acs.biomac.5c00300. Epub 2025 Jun 4.
Implantable biomedical supercapacitors represent a critical advancement in modern biomedical engineering, offering an optimal power solution for implantable medical devices due to their exceptional characteristics. However, achieving supercapacitors that concurrently exhibit tissue adhesiveness and biocompatibility remains a significant research challenge. In this study, the DMSO post-treatment method is employed to enhance the condensed state structure of the conductive polymer PEDOT:PSS, which results in a significant improvement in the electrochemical performance of the supercapacitor embedded within the poly(acrylic acid) hydrogel matrix. This supercapacitor demonstrates a capacity retention rate of 97.81% after 10 000 charging-discharging cycles. Additionally, it exhibits favorable mechanical properties (tensile strain of 233%) and strong tissue adhesiveness (viscous frictional stress of 6.42 kPa). Following implantation in mice, this device also exhibits excellent biocompatibility. These findings suggest that this technology can significantly advance the energy supply for microintelligent medical devices.
可植入生物医学超级电容器是现代生物医学工程的一项关键进展，因其卓越特性为可植入医疗设备提供了最佳的供电解决方案。然而，实现同时具备组织粘附性和生物相容性的超级电容器仍然是一项重大的研究挑战。在本研究中，采用二甲基亚砜后处理方法来增强导电聚合物聚（3,4-乙撑二氧噻吩）：聚苯乙烯磺酸盐（PEDOT:PSS）的凝聚态结构，这使得嵌入聚丙烯酸水凝胶基质中的超级电容器的电化学性能得到显著改善。该超级电容器在10000次充放电循环后容量保持率为97.81%。此外，它还表现出良好的机械性能（拉伸应变达233%）和较强的组织粘附性（粘性摩擦应力为6.42 kPa）。在小鼠体内植入后，该装置也表现出优异的生物相容性。这些发现表明，这项技术可显著推动微智能医疗设备的能量供应。
