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甲状腺肿指数:一种用于自身免疫性甲状腺疾病中甲状腺体积的易于获取的超声检查指数。

Goiter index: an easily available ultrasonographic index for thyroid volume in autoimmune thyroid diseases.

作者信息

Murakami Tsukasa, Higaki Naoyuki, Nishijima Yui, Tani Junichi, Noguchi Hitoshi, Eto Misako

机构信息

Department of Endocrinology, Noguchi Thyroid Clinic and Hospital Foundation, Oita 874-0902, Japan.

Department of Laboratory Medicine, Noguchi Thyroid Clinic and Hospital Foundation, Oita 874-0902, Japan.

出版信息

Endocr J. 2025 Aug 1;72(8):959-964. doi: 10.1507/endocrj.EJ25-0070. Epub 2025 Jun 3.

Abstract

This study aimed to confirm the applicability of the product of depth and width of the right thyroid lobe measured by ultrasonography, as an index of estimated thyroid volume in patients with Hashimoto thyroiditis. This study included 118 patients with Hashimoto thyroiditis and 163 patients with Graves' disease. The product of depth and width of the right thyroid lobe ranged from 1.7 to 10.2 (median, 4.4) cm for Hashimoto thyroiditis and 2.6 to 10.8 (median, 5.8) cm for Graves' disease. The estimated volume obtained by ellipsoidal approximation correlated well with the product of depth and width of the right thyroid lobe in Hashimoto thyroiditis (ρ = 0.820, p < 0.0001) and Graves' disease (ρ = 0.928, p < 0.0001), respectively. However, the correlations were not identical. The comparison of 72 patients with Hashimoto thyroiditis and 72 patients with Graves' disease who were matched for the product of depth and width revealed no significant difference in the estimated thyroid volume. These results show that the product of depth and width of the right thyroid lobe can be applied to indicate thyroid volume instead of the estimated volume obtained from ellipsoidal approximation in both Hashimoto thyroiditis and Graves' disease within the range of volumes investigated in this study.

摘要

本研究旨在证实超声测量的右甲状腺叶深度与宽度的乘积作为桥本甲状腺炎患者甲状腺估计体积指标的适用性。本研究纳入了118例桥本甲状腺炎患者和163例格雷夫斯病患者。桥本甲状腺炎患者右甲状腺叶深度与宽度的乘积范围为1.7至10.2(中位数为4.4)cm,格雷夫斯病患者为2.6至10.8(中位数为5.8)cm。通过椭球体近似法获得的估计体积与桥本甲状腺炎(ρ = 0.820,p < 0.0001)和格雷夫斯病(ρ = 0.928,p < 0.0001)患者右甲状腺叶深度与宽度的乘积分别具有良好的相关性。然而,相关性并不相同。对72例右甲状腺叶深度与宽度乘积匹配的桥本甲状腺炎患者和72例格雷夫斯病患者进行比较,发现甲状腺估计体积无显著差异。这些结果表明,在本研究调查的体积范围内,右甲状腺叶深度与宽度的乘积可用于指示桥本甲状腺炎和格雷夫斯病患者的甲状腺体积,而无需从椭球体近似法获得估计体积。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de0d/12340251/d73a68a61136/72_EJ25-0070_01.jpg

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