Krupnikovic Kosta S, Obradovic Danilo, Ilic Ivan, Dobric Milan
Institute for Cardiovascular Diseases 'Dedinje', University of Belgrade, Belgrade, Serbia.
Department of Internal Medicine and Cardiology, Herzzentrum Dresden, Technische Universität Dresden, Dresden, Germany.
Front Cardiovasc Med. 2025 May 21;12:1471211. doi: 10.3389/fcvm.2025.1471211. eCollection 2025.
Coronary artery anomalies (CAAs) are a rare congenital condition and represent additional challenges in interventional treatment of coronary artery disease.
A 76-year-old male, was admitted for elective coronary angiography due to symptoms of typical angina. CT coronary angiography (CTCA) revealed all three coronary arteries arising from the right sinus of Valsalva, where right coronary artery (RCA) and left anterior descending artery (LAD) had common ostium with significant stenosis of ostio-proximal RCA and circumflex artery (CX) coming from a separate one. Percutaneous coronary intervention (PCI) of ostial RCA was planned and intravascular ultrasound (IVUS) in both RCA and LAD was done. Due to extensive calcification, prior to intended PCI, intravascular lithotripsy (IVL) was done. Following IVL and extensive predilatation drug eluting stent (DES) was implanted. Final IVUS was used to confirm optimal stent deployment in proximal RCA and to verify that LAD ostium was not compromised with RCA stent. Six months later, due to angina and positive stress test, repeated coronary angiography revealed a restenosis of the ostial RCA so the lesion was again treated with drug-coated balloon with optimal procedural results.
Although rare, CAAs could be associated with coronary artery disease and usually present additional challenge for interventional treatment. Advanced imaging modalities, including CTCA and IVUS, provide good procedural guidance during complex PCI procedures in patients with CAAs.
冠状动脉异常(CAA)是一种罕见的先天性疾病,在冠状动脉疾病的介入治疗中带来了额外挑战。
一名76岁男性因典型心绞痛症状入院接受择期冠状动脉造影。CT冠状动脉造影(CTCA)显示所有三支冠状动脉均起源于主动脉窦右窦,其中右冠状动脉(RCA)和左前降支动脉(LAD)有共同开口,开口近端RCA严重狭窄,回旋支动脉(CX)起源于单独开口。计划对RCA开口进行经皮冠状动脉介入治疗(PCI),并对RCA和LAD进行血管内超声(IVUS)检查。由于广泛钙化,在预期的PCI之前,进行了血管内碎石术(IVL)。在IVL和广泛预扩张后,植入了药物洗脱支架(DES)。最终IVUS用于确认RCA近端支架的最佳植入,并验证LAD开口未受RCA支架影响。六个月后,由于心绞痛和负荷试验阳性进行重复冠状动脉造影,显示RCA开口再狭窄,因此再次用药物涂层球囊治疗该病变,手术结果理想。
尽管CAA罕见,但可能与冠状动脉疾病相关,通常给介入治疗带来额外挑战。包括CTCA和IVUS在内先进成像方式,可为CAA患者复杂PCI手术提供良好的手术指导。