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病例报告:多发性原发性双侧肺良性脊索细胞瘤合并骶骨肿瘤。

Case Report: Multiple primary bilateral lung benign notochord cell tumors combined with sacral tumors.

作者信息

Tao Minjia, Gao Peijun, Liu Jiajie, Zhang Biao, Tao Guowei

机构信息

Department of Thoracic Surgery, Haiyan People's Hospital, Jiaxing, Zhejiang, China.

Department of Pathology, Haiyan People's Hospital, Jiaxing, Zhejiang, China.

出版信息

Front Oncol. 2025 May 21;15:1537943. doi: 10.3389/fonc.2025.1537943. eCollection 2025.

Abstract

Benign notochord cell tumor (BNCT) in the bilateral lungs is exceedingly rare. This report details a case of a male patient diagnosed with primary bilateral lung BNCTs and concurrent sacral tumors. As part of a routine health check-up, a chest CT revealed suspicious nodules in both lungs. We performed a thoracoscopic wedge resection of the nodules on him. The postoperative pathological findings combined with CT and clinical manifestations confirmed BNCT. Post-operatively, considering that BNCT commonly occurs in the axial skeleton, we conducted an examination of the spine. Spinal CT and MRI revealed suspicious sacral lesions in the S3 to S5 vertebrae, necessitating further investigation and continuous follow-up monitoring. The simultaneous occurrence of primary multifocal pulmonary BNCTs coexisting with sacral tumors has never been reported before. Fully taking into account potential associations with other diseases, careful follow-up and a comprehensive diagnostic approach are essential for patients with pulmonary nodules.

摘要

双侧肺部的良性脊索细胞瘤(BNCT)极为罕见。本报告详细介绍了一例男性患者,该患者被诊断为原发性双侧肺部BNCT并伴有骶骨肿瘤。作为常规健康检查的一部分,胸部CT显示双肺有可疑结节。我们对他进行了胸腔镜下结节楔形切除术。术后病理结果结合CT和临床表现确诊为BNCT。术后,考虑到BNCT常见于中轴骨骼,我们对脊柱进行了检查。脊柱CT和MRI显示S3至S5椎体有可疑骶骨病变,需要进一步检查和持续随访监测。原发性多灶性肺部BNCT与骶骨肿瘤同时出现此前从未有过报道。充分考虑与其他疾病的潜在关联,对肺部结节患者进行仔细随访和全面的诊断方法至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/4a85f32361ab/fonc-15-1537943-g001.jpg

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