• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

病例报告:多发性原发性双侧肺良性脊索细胞瘤合并骶骨肿瘤。

Case Report: Multiple primary bilateral lung benign notochord cell tumors combined with sacral tumors.

作者信息

Tao Minjia, Gao Peijun, Liu Jiajie, Zhang Biao, Tao Guowei

机构信息

Department of Thoracic Surgery, Haiyan People's Hospital, Jiaxing, Zhejiang, China.

Department of Pathology, Haiyan People's Hospital, Jiaxing, Zhejiang, China.

出版信息

Front Oncol. 2025 May 21;15:1537943. doi: 10.3389/fonc.2025.1537943. eCollection 2025.

DOI:10.3389/fonc.2025.1537943
PMID:40469192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12133830/
Abstract

Benign notochord cell tumor (BNCT) in the bilateral lungs is exceedingly rare. This report details a case of a male patient diagnosed with primary bilateral lung BNCTs and concurrent sacral tumors. As part of a routine health check-up, a chest CT revealed suspicious nodules in both lungs. We performed a thoracoscopic wedge resection of the nodules on him. The postoperative pathological findings combined with CT and clinical manifestations confirmed BNCT. Post-operatively, considering that BNCT commonly occurs in the axial skeleton, we conducted an examination of the spine. Spinal CT and MRI revealed suspicious sacral lesions in the S3 to S5 vertebrae, necessitating further investigation and continuous follow-up monitoring. The simultaneous occurrence of primary multifocal pulmonary BNCTs coexisting with sacral tumors has never been reported before. Fully taking into account potential associations with other diseases, careful follow-up and a comprehensive diagnostic approach are essential for patients with pulmonary nodules.

摘要

双侧肺部的良性脊索细胞瘤(BNCT)极为罕见。本报告详细介绍了一例男性患者,该患者被诊断为原发性双侧肺部BNCT并伴有骶骨肿瘤。作为常规健康检查的一部分,胸部CT显示双肺有可疑结节。我们对他进行了胸腔镜下结节楔形切除术。术后病理结果结合CT和临床表现确诊为BNCT。术后,考虑到BNCT常见于中轴骨骼,我们对脊柱进行了检查。脊柱CT和MRI显示S3至S5椎体有可疑骶骨病变,需要进一步检查和持续随访监测。原发性多灶性肺部BNCT与骶骨肿瘤同时出现此前从未有过报道。充分考虑与其他疾病的潜在关联,对肺部结节患者进行仔细随访和全面的诊断方法至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/9651c50590e2/fonc-15-1537943-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/4a85f32361ab/fonc-15-1537943-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/e4347ba9e594/fonc-15-1537943-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/186e24617dc9/fonc-15-1537943-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/9651c50590e2/fonc-15-1537943-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/4a85f32361ab/fonc-15-1537943-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/e4347ba9e594/fonc-15-1537943-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/186e24617dc9/fonc-15-1537943-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/81c5/12133830/9651c50590e2/fonc-15-1537943-g004.jpg

相似文献

1
Case Report: Multiple primary bilateral lung benign notochord cell tumors combined with sacral tumors.病例报告:多发性原发性双侧肺良性脊索细胞瘤合并骶骨肿瘤。
Front Oncol. 2025 May 21;15:1537943. doi: 10.3389/fonc.2025.1537943. eCollection 2025.
2
Intraosseous benign notochord cell tumors (BNCT): further evidence supporting a relationship to chordoma.骨内良性脊索细胞瘤(BNCT):支持与脊索瘤存在关联的进一步证据。
Am J Surg Pathol. 2007 Oct;31(10):1573-7. doi: 10.1097/PAS.0b013e31805c9967.
3
Benign notochordal cell tumors of the spine: natural history of 8 patients with histologically confirmed lesions.脊柱良性脊索细胞肿瘤:8 例组织学证实病变患者的自然病史。
Neurosurgery. 2013 Sep;73(3):411-6. doi: 10.1227/01.neu.0000431476.94783.c6.
4
Simultaneous bilateral pulmonary resection via single-utility port VATS for multiple pulmonary nodules: A single-center experience of 16 cases.单孔胸腔镜下单发式双侧肺结节切除术:单中心 16 例经验
Thorac Cancer. 2021 Feb;12(4):525-533. doi: 10.1111/1759-7714.13791. Epub 2020 Dec 22.
5
Multiple benign notochordal cell tumors in lung with cystic change.肺内多发良性脊索细胞瘤伴囊性变
Radiol Case Rep. 2023 Jun 24;18(9):3117-3121. doi: 10.1016/j.radcr.2023.06.014. eCollection 2023 Sep.
6
Difficulty distinguishing benign notochordal cell tumor from chordoma further suggests a link between them.难以区分良性脊索细胞瘤与脊索瘤这一情况进一步表明了它们之间的联系。
Cancer Imaging. 2014 Apr 22;14(1):4. doi: 10.1186/1470-7330-14-4.
7
Benign notochordal cell tumor: a retrospective study of 11 cases with 13 vertebra bodies.
Int J Clin Exp Pathol. 2014 Jun 15;7(7):3548-54. eCollection 2014.
8
Pulmonary tumor with notochordal differentiation: report of 2 cases suggestive of benign notochordal cell tumor of extraosseous origin.具有脊索分化的肺肿瘤:2 例提示源自骨外的良性脊索细胞肿瘤的报告。
Am J Surg Pathol. 2011 Aug;35(8):1158-64. doi: 10.1097/PAS.0b013e318220e085.
9
Extraosseous benign notochordal cell tumor originating in the lung: a case report.起源于肺部的骨外良性脊索细胞瘤:一例报告
Medicine (Baltimore). 2015 Jan;94(1):e366. doi: 10.1097/MD.0000000000000366.
10
Multiple primary chordomas of the lung.肺多发性原发性脊索瘤。
Respir Med Case Rep. 2018 Aug 21;25:142-144. doi: 10.1016/j.rmcr.2018.08.012. eCollection 2018.

本文引用的文献

1
Benign Notochordal Cell Tumours: Case Report and Literature Review.良性脊索细胞瘤:病例报告及文献综述
Diagnostics (Basel). 2024 Jun 23;14(13):1330. doi: 10.3390/diagnostics14131330.
2
[Well Differentiated Liposarcoma of a Lung:Report of a Case].[肺高分化脂肪肉瘤:一例报告]
Kyobu Geka. 2024 Mar;77(3):230-234.
3
Evaluating the Patient With a Pulmonary Nodule: A Review.评估肺部结节患者:综述。
JAMA. 2022 Jan 18;327(3):264-273. doi: 10.1001/jama.2021.24287.
4
Isolated Solitary Lung Nodule in a Patient With Idiopathic Pulmonary Fibrosis and Concomitant Prostate Cancer: A Challenging Diagnosis.一名特发性肺纤维化合并前列腺癌患者的孤立性肺结节:一项具有挑战性的诊断。
Cureus. 2021 Mar 31;13(3):e14218. doi: 10.7759/cureus.14218.
5
Updates from the 2020 World Health Organization Classification of Soft Tissue and Bone Tumours.2020 年世界卫生组织软组织和骨肿瘤分类更新。
Histopathology. 2021 Apr;78(5):644-657. doi: 10.1111/his.14265. Epub 2021 Jan 12.
6
Benign notochordal cell tumor of the lung: Report of a case.肺良性脊索细胞肿瘤:病例报告。
Pathol Int. 2020 Nov;70(11):871-875. doi: 10.1111/pin.13005. Epub 2020 Aug 22.
7
A case of Löfgren's syndrome confused with decompression sickness.一例被误诊为减压病的洛弗格伦综合征病例。
Diving Hyperb Med. 2019 Dec 20;49(4):306-310. doi: 10.28920/dhm49.4.306-310.
8
Systematic Review of Clinical, Radiologic, and Histologic Features of Benign Notochordal Cell Tumors: Implications for Patient Management.良性脊索细胞肿瘤的临床、放射学和组织学特征的系统评价:对患者管理的影响。
World Neurosurg. 2019 Oct;130:13-23. doi: 10.1016/j.wneu.2019.06.009. Epub 2019 Jun 14.
9
Benign notochordal cell tumour: clinicopathology and molecular profiling of 13 cases.良性脊索细胞肿瘤:13 例的临床病理和分子特征分析。
J Clin Pathol. 2019 Jan;72(1):66-74. doi: 10.1136/jclinpath-2018-205441. Epub 2018 Oct 24.
10
Solitary pulmonary caseating granulomas: A 5-year retrospective single-center analysis.孤立性肺干酪样肉芽肿:一项为期5年的回顾性单中心分析。
Mol Clin Oncol. 2017 Jun;6(6):839-845. doi: 10.3892/mco.2017.1244. Epub 2017 May 8.