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冷冻消融术作为局部复发性甲状腺癌患者的局部治疗:两例病例报告。

Cryoablation as local therapy in patients with locally recurrent thyroid cancer: Two case reports.

作者信息

Simon Sorina R, Lubbers Tim, Engelen Sanne, de Boer Sanne W, van der Leij Christiaan

机构信息

Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht 6229 HX, The Netherlands.

GROW-School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.

出版信息

Radiol Case Rep. 2025 May 8;20(7):3617-3620. doi: 10.1016/j.radcr.2025.04.065. eCollection 2025 Jul.

Abstract

The local surgical treatment of thyroid cancer recurrence poses significant challenges, particularly when addressing areas affected by extensive scar tissue. Cryoablation of local recurrences might be a promising minimally invasive alternative, especially for patients who are not ideal surgical candidates or prefer nonsurgical interventions. This report discusses 2 cases of recurrent thyroid cancer successfully managed with curative intent cryoablation. Follow-up ultrasound revealed complete involution in the first patient, and 73% volume reduction of the lesion in the second patient. No delayed complications were observed. It underlines the potential of cryoablation as a feasible treatment option for local recurrence of thyroid cancer and advocates for future research to better define its role within thyroid cancer management protocols.

摘要

甲状腺癌复发的局部手术治疗面临重大挑战,尤其是在处理受广泛瘢痕组织影响的区域时。局部复发灶的冷冻消融可能是一种有前景的微创替代方法,特别是对于那些并非理想手术候选者或倾向于非手术干预的患者。本报告讨论了2例采用根治性冷冻消融成功治疗的复发性甲状腺癌病例。随访超声显示,首例患者病灶完全消退,第二例患者病灶体积缩小73%。未观察到延迟并发症。这凸显了冷冻消融作为甲状腺癌局部复发可行治疗选择的潜力,并提倡未来开展研究以更好地明确其在甲状腺癌治疗方案中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e02/12134475/9be6a66232e3/gr1.jpg

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