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冷冻消融术作为局部复发性甲状腺癌患者的局部治疗:两例病例报告。

Cryoablation as local therapy in patients with locally recurrent thyroid cancer: Two case reports.

作者信息

Simon Sorina R, Lubbers Tim, Engelen Sanne, de Boer Sanne W, van der Leij Christiaan

机构信息

Department of Radiology and Nuclear Medicine, Maastricht University Medical Center, Maastricht 6229 HX, The Netherlands.

GROW-School for Oncology and Reproduction, Maastricht University, Maastricht, The Netherlands.

出版信息

Radiol Case Rep. 2025 May 8;20(7):3617-3620. doi: 10.1016/j.radcr.2025.04.065. eCollection 2025 Jul.

DOI:10.1016/j.radcr.2025.04.065
PMID:40469263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12134475/
Abstract

The local surgical treatment of thyroid cancer recurrence poses significant challenges, particularly when addressing areas affected by extensive scar tissue. Cryoablation of local recurrences might be a promising minimally invasive alternative, especially for patients who are not ideal surgical candidates or prefer nonsurgical interventions. This report discusses 2 cases of recurrent thyroid cancer successfully managed with curative intent cryoablation. Follow-up ultrasound revealed complete involution in the first patient, and 73% volume reduction of the lesion in the second patient. No delayed complications were observed. It underlines the potential of cryoablation as a feasible treatment option for local recurrence of thyroid cancer and advocates for future research to better define its role within thyroid cancer management protocols.

摘要

甲状腺癌复发的局部手术治疗面临重大挑战,尤其是在处理受广泛瘢痕组织影响的区域时。局部复发灶的冷冻消融可能是一种有前景的微创替代方法,特别是对于那些并非理想手术候选者或倾向于非手术干预的患者。本报告讨论了2例采用根治性冷冻消融成功治疗的复发性甲状腺癌病例。随访超声显示,首例患者病灶完全消退,第二例患者病灶体积缩小73%。未观察到延迟并发症。这凸显了冷冻消融作为甲状腺癌局部复发可行治疗选择的潜力,并提倡未来开展研究以更好地明确其在甲状腺癌治疗方案中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e02/12134475/547698570fad/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e02/12134475/9be6a66232e3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e02/12134475/547698570fad/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e02/12134475/9be6a66232e3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e02/12134475/547698570fad/gr2.jpg

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本文引用的文献

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Percutaneous cryoablation in soft tissue tumor management: an educational review.经皮冷冻消融在软组织肿瘤治疗中的应用:一篇教育综述。
Insights Imaging. 2024 Nov 18;15(1):278. doi: 10.1186/s13244-024-01822-5.
2
Surgical resection of recurrent differentiated thyroid cancer: patterns, detection, staging, and treatment of 683 patients.683 例复发性分化型甲状腺癌的外科治疗:模式、检测、分期和治疗。
Front Endocrinol (Lausanne). 2023 Dec 6;14:1301620. doi: 10.3389/fendo.2023.1301620. eCollection 2023.
3
Salvage Cryoablation for Local Recurrences of Thyroid Cancer Inseparable from the Trachea and Neurovascular Structures.
挽救性冷冻消融术治疗与气管和神经血管结构无法分离的甲状腺癌局部复发
J Vasc Interv Radiol. 2023 Jan;34(1):54-62. doi: 10.1016/j.jvir.2022.10.001. Epub 2022 Oct 8.
4
Percutaneous Cryoablation for Recurrent Head and Neck Tumors.经皮冷冻消融治疗头颈部复发性肿瘤。
Cardiovasc Intervent Radiol. 2022 Jun;45(6):791-799. doi: 10.1007/s00270-022-03120-3. Epub 2022 Apr 4.
5
Recurred Post-intubation Tracheal Stenosis Treated with Bronchoscopic Cryotherapy.经支气管镜冷冻治疗复发性气管插管后狭窄
Intern Med. 2016;55(22):3331-3335. doi: 10.2169/internalmedicine.55.6421. Epub 2016 Nov 15.
6
Percutaneous Image-Guided Cryoablation of Head and Neck Tumors for Local Control, Preservation of Functional Status, and Pain Relief.经皮影像引导下对头颈部肿瘤进行冷冻消融以实现局部控制、保留功能状态并缓解疼痛。
AJR Am J Roentgenol. 2017 Feb;208(2):453-458. doi: 10.2214/AJR.16.16446. Epub 2016 Nov 15.