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采用腹壁下深动脉穿支皮瓣即刻乳房重建术后手术部位感染

Surgical Site Infection Owing to After Immediate Breast Reconstruction Using a Deep Inferior Epigastric Perforator Flap.

作者信息

Suzuki Anna, Komiya Takako, Fujita Hiroaki, Shimada Kazuki, Nonaka Masahito, Hanano Mai, Takeishi Meisei, Ishikawa Takashi, Matsumura Hajime

机构信息

From the Department of Plastic and Reconstructive Surgery, Tokyo Medical University, Tokyo, Japan.

Department of Infection Prevention and Control, Tokyo Medical University, Tokyo, Japan.

出版信息

Plast Reconstr Surg Glob Open. 2025 Jun 4;13(6):e6823. doi: 10.1097/GOX.0000000000006823. eCollection 2025 Jun.

DOI:10.1097/GOX.0000000000006823
PMID:40469556
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12136667/
Abstract

is a rare, rapidly growing, nontuberculosis mycobacterium that belongs to type IV of the rapidly growing mycobacteria. These bacteria are found in soil and water, and cause localized skin and soft tissue infections; however, they are challenging to culture, leading to diagnostic delays. To our knowledge, there have been 12 reported cases of surgical site infections (SSIs) caused by , with only 2 cases following breast reconstruction. A 51-year-old woman underwent nipple-sparing mastectomy and immediate breast reconstruction using a deep inferior epigastric perforator flap for invasive ductal carcinoma of the left breast. One month after surgery, she developed an SSI caused by . Despite initial outpatient treatment, the infection persisted, requiring multiple hospitalizations, administration of intravenous antibiotics, and several debridements under general anesthesia. Negative pressure wound therapy and a coordinated approach among various medical specialties are essential for managing infections. The patient experienced side effects from prolonged antibiotic use but eventually exhibited no signs of infection recurrence. This case highlights the challenges in diagnosing and treating SSIs, emphasizing the need for comprehensive surgical and medical management, together with patient-centered care, to effectively manage long-term treatment.

摘要

是一种罕见的、生长迅速的非结核分枝杆菌,属于快速生长分枝杆菌的IV型。这些细菌存在于土壤和水中,可引起局部皮肤和软组织感染;然而,它们的培养具有挑战性,会导致诊断延迟。据我们所知,已有12例由引起的手术部位感染(SSI)的报告,其中仅有2例发生在乳房重建术后。一名51岁女性因左乳浸润性导管癌接受了保留乳头的乳房切除术,并使用腹壁下深动脉穿支皮瓣立即进行乳房重建。术后1个月,她发生了由引起的SSI。尽管最初进行了门诊治疗,但感染持续存在,需要多次住院、静脉使用抗生素以及在全身麻醉下进行多次清创。负压伤口治疗以及各医学专科之间的协作方法对于管理感染至关重要。患者因长期使用抗生素出现了副作用,但最终未表现出感染复发的迹象。该病例凸显了诊断和治疗SSI的挑战,强调需要全面的手术和医疗管理以及以患者为中心的护理,以有效管理长期治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44fd/12136667/fd2db6882f4d/gox-13-e6823-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44fd/12136667/fb05ff0aa8a5/gox-13-e6823-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44fd/12136667/fd2db6882f4d/gox-13-e6823-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44fd/12136667/fb05ff0aa8a5/gox-13-e6823-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44fd/12136667/fd2db6882f4d/gox-13-e6823-g002.jpg

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本文引用的文献

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Successful management of surgical site infection caused by Mycobacterium mageritense in a breast cancer patient.成功治疗一例乳腺癌患者由马格李斯特分枝杆菌引起的手术部位感染。
J Infect Chemother. 2024 Aug;30(8):800-805. doi: 10.1016/j.jiac.2024.01.014. Epub 2024 Jan 23.
2
A Ventral Hernia-repair-related Mesh Infection Treated with NPWT without Mesh Removal.经负压伤口治疗(NPWT)处理且未移除补片的腹疝修补相关补片感染
Plast Reconstr Surg Glob Open. 2021 Sep 7;9(9):e3799. doi: 10.1097/GOX.0000000000003799. eCollection 2021 Sep.
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Mycobacterium mageritense causing surgical site infection: Case report from Odisha, India.
导致手术部位感染的马格李斯特分枝杆菌:来自印度奥里萨邦的病例报告。
Indian J Med Microbiol. 2021 Jul;39(3):389-391. doi: 10.1016/j.ijmmb.2021.04.008. Epub 2021 May 14.
4
infection following mastectomy and breast reconstruction requiring triple antibiotic therapy and surgical debridement.乳房切除术后和乳房重建术后感染,需要三联抗生素治疗和外科清创。
BMJ Case Rep. 2021 Feb 4;14(2):e237618. doi: 10.1136/bcr-2020-237618.
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Prosthetic Joint Infection.人工关节感染
Case Rep Infect Dis. 2020 Jul 11;2020:8845430. doi: 10.1155/2020/8845430. eCollection 2020.
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Multiple Recalcitrant Draining Sinuses Caused by Mycobacterium mageritense Following Laparoscopic Cholecystectomy: a Case Report and Brief Review of Literature.腹腔镜胆囊切除术后由马格里滕分枝杆菌引起的多发性顽固性引流性窦道:一例报告并文献简要回顾
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Implantable cardioverter defibrillator infection due to Mycobacterium mageritense.因马格里滕斯分枝杆菌导致的植入式心脏复律除颤器感染。
J Infect Chemother. 2016 Mar;22(3):180-3. doi: 10.1016/j.jiac.2015.09.010. Epub 2015 Dec 21.
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Mycobacterium mageritense sp. nov.马格里特分枝杆菌新种
Int J Syst Bacteriol. 1997 Apr;47(2):535-40. doi: 10.1099/00207713-47-2-535.