Basimah Albalooshy, Faro Scott Scott, Yuan Hsiangkuo, Talekar Kiran, Mondel Prabath, Qiu Enchao, Chaganti Joga
Department of Radiology, Thomas Jefferson University, Philadelphia, PA, United States.
Jefferson Headache Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA, United States.
Front Radiol. 2025 May 21;5:1605777. doi: 10.3389/fradi.2025.1605777. eCollection 2025.
Idiopathic Intracranial hypertension (IIH), also referred to as pseudotumor cerebri, is a term used to describe increased intracranial pressure in the absence of a known identifiable secondary cause. Despite advancements of neuroimaging techniques, imaging of the pathological underpinnings in the diagnosis of IIH has been limited. Although the causation of IIH has been ascribed to increased Cerebrospinal Fluid production and disordered drainage through the dural sinuses, new evidence shows that the glymphatic system which is an alternate pathway of drainage is likely to play a pivotal role. In this review, we address the pathophysiological underpinnings in the causation of IIH and discusses characteristic anatomical imaging findings on conventional MRI and explore the role of advanced imaging techniques.
特发性颅内高压（IIH），也称为假性脑瘤，是一个用于描述在没有已知可识别的继发原因的情况下颅内压升高的术语。尽管神经成像技术有所进步，但IIH诊断中病理基础的成像一直有限。虽然IIH的病因被归因于脑脊液产生增加和通过硬脑膜窦的引流紊乱，但新证据表明，作为另一种引流途径的淋巴系统可能起关键作用。在这篇综述中，我们阐述了IIH病因中的病理生理基础，讨论了传统MRI上的特征性解剖成像表现，并探讨了先进成像技术的作用。
