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真实世界中人工智能驱动的分割:放射治疗中的效率提升与工作流程挑战

Real world AI-driven segmentation: Efficiency gains and workflow challenges in radiotherapy.

作者信息

Malone Ciaran, Nicholson Jill, Ryan Samantha, Thirion Pierre, Woods Ruth, McBride Peter, McArdle Orla, Duane Frances, Hanna Gerard G, McClean Brendan, Brennan Sinead

机构信息

St.Luke's Radiation Oncology Network, Dublin, Ireland.

St.Luke's Radiation Oncology Network, Dublin, Ireland; Applied Radiation Therapy Trinity, Discipline of Radiation Therapy & Trinity St James's Cancer Institute, Trinity College Dublin, Dublin, Ireland.

出版信息

Radiother Oncol. 2025 Aug;209:110977. doi: 10.1016/j.radonc.2025.110977. Epub 2025 Jun 3.

DOI:10.1016/j.radonc.2025.110977
PMID:40472996
Abstract

BACKGROUND

It remains unclear whether improving contouring efficiency using AI-driven contouring (AIseg) significantly shortens the OAR contouring task time in a real world setting, or the overall radiotherapy planning-CT to treatment time. This single institution multidisciplinary study aims to evaluate how AIseg changes the duration taken for contouring tasks as well as the time to complete the overall treatment planning carepath from planning CT to treatment start.

METHODS

This retrospective study evaluated both palliative and radical radiotherapy OAR contouring time metrics in a large, real-world patient cohort across four years. Data included both conventional and ablative radiation schedules. Data on task availability, initiation, and completion were recorded from ARIA patient records across a four-year period: three years before (pre-AI) and one year after AI implementation (post-AI). "In-progress" OAR contouring times (from task initiation to completion) and OAR contouring workflow times (from task availability to completion) were analysed across multiple anatomical sites, including head and neck, thorax, abdomen, breast, and pelvis. Trends were assessed monthly to determine if any immediate (step) or gradual (slope) changes associated with AIseg introduction occurred. Additionally, overall CT-to-treatment intervals were evaluated to see if contouring efficiencies translated into shorter CT-to-treatment workflows.

RESULTS

A total of 9,964 pre-AI and 3,820 post-AI OAR contouring "in-progress" tasks were analysed, alongside 16,352 pre-AI and 5,870 post-AI "workflow" tasks. AIseg consistently reduced median active contouring times 51.5 % (p < 0.001), and up to 70 % in the most complex cohorts (e.g., head and neck, thorax). Month-by-month trend analyses showed that prior to AIseg, contouring workflow times trended upward. Post-AIseg, these same trends gradually improved and sloped downward (p < 0.001). Despite these notable gains at the task and workflow levels, there was no corresponding decrease in overall CT-to-treatment intervals. However, in the post-AI period, a significantly higher proportion of plans were approved and ready for treatment.

CONCLUSION

AIseg offers substantial efficiency gains in active contouring, particularly for complex cases, and resulted in increasing improvements in contouring workflow times over the post-implementation period. Although overall CT-to-treatment timelines remained unchanged due to fixed scheduling constraints, a significantly greater proportion of plans were ready earlier post-AIseg implementation. Our study challenges the assumption that task-level efficiencies automatically translate into faster overall patient treatment pathways, underscoring the critical need for deliberate workflow and scheduling optimisation to ensure that time savings yield meaningful improvements in patient timelines and outcomes.

摘要

背景

在实际应用中,利用人工智能驱动的轮廓勾画技术(AIseg)提高轮廓勾画效率是否能显著缩短危及器官(OAR)轮廓勾画任务时间,或缩短从放疗计划CT到治疗开始的整个放疗计划时间,目前尚不清楚。这项单机构多学科研究旨在评估AIseg如何改变轮廓勾画任务所需的时间,以及完成从计划CT到治疗开始的整个治疗计划流程的时间。

方法

这项回顾性研究评估了四年间一个大型真实世界患者队列中姑息性和根治性放疗的OAR轮廓勾画时间指标。数据包括传统放疗和消融放疗方案。在四年期间,从ARIA患者记录中记录任务的可用性、启动和完成情况:AI实施前三年(AI前)和AI实施后一年(AI后)。分析了多个解剖部位(包括头颈部、胸部、腹部、乳腺和骨盆)的“进行中”OAR轮廓勾画时间(从任务启动到完成)和OAR轮廓勾画工作流程时间(从任务可用到完成)。每月评估趋势,以确定是否发生了与引入AIseg相关的任何即时(阶跃)或渐进(斜率)变化。此外,评估了从CT到治疗的总间隔时间,以查看轮廓勾画效率是否转化为更短的从CT到治疗的工作流程。

结果

共分析了9964项AI前和3820项AI后的OAR轮廓勾画“进行中”任务,以及16352项AI前和5870项AI后的“工作流程”任务。AIseg持续将中位有效轮廓勾画时间减少了51.5%(p<0.001),在最复杂的队列(如头颈部、胸部)中最多减少了70%。逐月趋势分析表明,在引入AIseg之前,轮廓勾画工作流程时间呈上升趋势。引入AIseg后,这些趋势逐渐改善并呈下降趋势(p<0.001)。尽管在任务和工作流程层面取得了这些显著进展,但从CT到治疗的总间隔时间并没有相应减少。然而,在AI后时期,获批并准备好进行治疗的计划比例显著更高。

结论

AIseg在有效轮廓勾画方面显著提高了效率,尤其是对于复杂病例,并且在实施后的时期内,轮廓勾画工作流程时间有了越来越大的改善。尽管由于固定的时间表限制,从CT到治疗的总体时间线保持不变,但在引入AIseg后,准备好的计划比例显著更高。我们的研究挑战了任务层面的效率会自动转化为更快的整体患者治疗路径这一假设,强调了精心设计工作流程和优化时间表的迫切需求,以确保节省的时间能为患者的时间线和治疗结果带来有意义的改善。

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