Ortega Florencia, Minnaard Jessica, Arce Valeria B, García M Alejandra
Centro de Investigación y Desarrollo en Ciencia y Tecnología de los Alimentos (CIDCA), (UNLP - CIC-PBA - CONICET), La Plata 1900, Argentina; Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata 1900, Argentina.
Centro de Investigación y Desarrollo en Ciencia y Tecnología de los Alimentos (CIDCA), (UNLP - CIC-PBA - CONICET), La Plata 1900, Argentina; Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata 1900, Argentina.
Int J Biol Macromol. 2025 Jul;318(Pt 1):144904. doi: 10.1016/j.ijbiomac.2025.144904. Epub 2025 Jun 3.
This study investigates the development of corn starch nanocomposite films containing silver nanoparticles (AgNPs) synthesized by ultra-short pulse Ti:Za laser (AgNP F) and compares them with films containing chemically synthesized AgNPs (AgNP in situ). AgNP F, formed in a 1 % w/v starch solution, exhibited a well-dispersed spherical morphology (3 nm radius), which was confirmed by UV-vis spectroscopy and TEM images. Both types of nanoparticles were successfully integrated into 3 % w/v starch film-forming suspensions, to obtain nanocomposite materials without structural defects, as observed by SEM. AgNP F films had an intense yellow hue compared to those with AgNPs in situ. The nanocomposite films exhibited improved mechanical, optical, and barrier properties, compared to the control starch films, which is critical for packaging applications. However, cytotoxicity assessments revealed that AgNP F films reduced Caco-2/TC7 cell viability to 66 %, whereas AgNP in situ films maintained 90 % viability. Both nanocomposite films affected the viability of Vero cells. These results demonstrate that AgNPs significantly improve the structural and functional properties of starch-based films, although biocompatibility is dependent on the synthesis method. This research advances biopolymer-based nanocomposites for sustainable packaging applications.
本研究调查了含有通过超短脉冲钛宝石激光合成的银纳米颗粒（AgNP F）的玉米淀粉纳米复合薄膜的发展情况，并将其与含有化学合成银纳米颗粒（原位AgNP）的薄膜进行比较。在1% w/v淀粉溶液中形成的AgNP F呈现出分散良好的球形形态（半径3纳米），这通过紫外可见光谱和透射电镜图像得到证实。通过扫描电子显微镜观察发现，两种类型的纳米颗粒都成功地整合到3% w/v淀粉成膜悬浮液中，以获得无结构缺陷的纳米复合材料。与含有原位AgNP的薄膜相比，AgNP F薄膜具有强烈的黄色色调。与对照淀粉薄膜相比，纳米复合薄膜表现出改善的机械、光学和阻隔性能，这对于包装应用至关重要。然而，细胞毒性评估显示，AgNP F薄膜将Caco-2/TC7细胞活力降低至66%，而原位AgNP薄膜保持90%的活力。两种纳米复合薄膜都影响了Vero细胞的活力。这些结果表明，银纳米颗粒显著改善了淀粉基薄膜的结构和功能特性，尽管生物相容性取决于合成方法。本研究推动了基于生物聚合物的纳米复合材料在可持续包装应用中的发展。
