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探索患者将富血小板血浆作为膝关节骨关节炎初级治疗方法的动机:焦点小组讨论

Exploring Patients' Motivations in Using Platelet-Rich Plasma as Their Primary Care Therapy for Managing Knee Osteoarthritis: A Focus Group Discussion.

作者信息

Pineda-Cortel Maria Ruth, Cabrera Jan Tyrone, Villavieja Adrian, Bernardo-Bueno Mary Monica, Daya Minerva, Alegre John Emil, Vergara Renz Cleve, Bonifacio Rinnel Brenan, Suarez Consuelo G

机构信息

Department of Medical Technology, Faculty of Pharmacy, University of Santo Tomas, Manila, Philippines.

Research Center for the Natural and Applied Sciences, University of Santo Tomas, Manila, Philippines.

出版信息

J Patient Exp. 2025 Jun 4;12:23743735251323387. doi: 10.1177/23743735251323387. eCollection 2025.

DOI:10.1177/23743735251323387
PMID:40474880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12138209/
Abstract

Knee osteoarthritis (KOA) is a degenerative disease that causes pain and burden in patients. Aside from surgery, clinicians tout the potential use of platelet-rich plasma. This study explores motivation in terms of perceptions, experiences, and recommendations of KOA patients who received platelet-rich plasma (PRP) as primary care therapy. A qualitative approach via focus group discussion was conducted. Data were analyzed using thematic analysis and visualized using MAXQDA. Patients' motivation for the use of PRP was based on three factors: (1) their perception of PRP as a therapy, (2) their lived experiences post-PRP therapy, and (3) their willingness to recommend PRP to others as a primary care therapy. The elements of each theme were identified and ranked based on how often the patients expressed the same thought, with willingness (f=5), alternative therapy (f=7), and pain (f=27) ranking highest. Physicians' recommendations, preference for a non-surgical approach, and later on, reduced pain and improved quality of life made them believe in the effectiveness of PRP as primary care therapy to alleviate KOA symptoms.

摘要

膝骨关节炎(KOA)是一种导致患者疼痛和负担的退行性疾病。除了手术之外,临床医生还大力推崇富血小板血浆的潜在用途。本研究从接受富血小板血浆(PRP)作为初级保健治疗的KOA患者的认知、经历和建议方面探讨其动机。通过焦点小组讨论采用了定性研究方法。使用主题分析法对数据进行分析,并使用MAXQDA进行可视化呈现。患者使用PRP的动机基于三个因素:(1)他们对PRP作为一种治疗方法的认知;(2)他们接受PRP治疗后的生活经历;(3)他们愿意将PRP作为初级保健治疗方法推荐给他人。根据患者表达相同想法的频率对每个主题的要素进行识别和排序,意愿(f = 5)、替代疗法(f = 7)和疼痛(f = 27)的排名最高。医生的建议、对非手术方法的偏好,以及随后疼痛减轻和生活质量改善,使他们相信PRP作为缓解KOA症状的初级保健治疗方法的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41f3/12138209/3c71808879bd/10.1177_23743735251323387-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41f3/12138209/3c71808879bd/10.1177_23743735251323387-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41f3/12138209/3c71808879bd/10.1177_23743735251323387-fig1.jpg

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本文引用的文献

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Platelet-Rich Plasma Therapy: An Effective Approach for Managing Knee Osteoarthritis.富血小板血浆疗法:一种治疗膝关节骨关节炎的有效方法。
Cureus. 2023 Dec 19;15(12):e50774. doi: 10.7759/cureus.50774. eCollection 2023 Dec.
2
A qualitative analysis of trust and distrust within patient-clinician interactions.医患互动中信任与不信任的定性分析。
PEC Innov. 2023 Jun 30;3:100187. doi: 10.1016/j.pecinn.2023.100187. eCollection 2023 Dec 15.
3
When are patients with osteoarthritis referred for surgery?当患者患有骨关节炎时,何时应进行手术?
Best Pract Res Clin Rheumatol. 2023 Jun;37(2):101835. doi: 10.1016/j.berh.2023.101835. Epub 2023 May 30.
4
Cost-Effectiveness of Arthroscopic Partial Meniscectomy and Physical Therapy for Degenerative Meniscal Tear.关节镜下半月板部分切除术及物理治疗对退行性半月板撕裂的成本效益分析
ACR Open Rheumatol. 2022 Oct;4(10):853-862. doi: 10.1002/acr2.11480. Epub 2022 Jul 21.
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New developments in osteoarthritis pharmacological therapies.骨关节炎药理学治疗的新进展。
Rheumatology (Oxford). 2021 Dec 24;60(Suppl 6):vi1-vi11. doi: 10.1093/rheumatology/keab679.
6
Emerging and New Treatment Options for Knee Osteoarthritis.膝关节骨关节炎的新兴和新治疗选择。
Curr Rheumatol Rev. 2022;18(1):20-32. doi: 10.2174/1573397117666211116111738.
7
Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies.基于人群研究的全球、地区膝关节骨关节炎的患病率、发病率及危险因素
EClinicalMedicine. 2020 Nov 26;29-30:100587. doi: 10.1016/j.eclinm.2020.100587. eCollection 2020 Dec.
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Case Report: Rehabilitation After Platelet-Rich Growth Factors' Intra-Articular Injections for Knee Osteoarthritis: Two Case Reports of a Home-Based Protocol.病例报告:富血小板生长因子关节内注射治疗膝关节骨关节炎后的康复:基于家庭方案的两例病例报告
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Clinical therapy of platelet-rich plasma vs hyaluronic acid injections in patients with knee osteoarthritis: A systematic review and meta-analysis of randomized double-blind controlled trials.富血小板血浆与透明质酸注射治疗膝骨关节炎的临床疗效:随机双盲对照试验的系统评价和荟萃分析。
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