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Overcoming borders: International cooperation in re-use and re-interpretation of omics data in Fontan circulation.

作者信息

Michel Miriam, Renaud David, Kelly Benjamin, Assi Ismael Z, Pei Liming, Opotowsky Alexander R

机构信息

Department of Child and Adolescent Health, Division of Pediatrics III-Cardiology, Pulmonology, Allergology and Cystic Fibrosis, Medical University of Innsbruck, 6020, Innsbruck, Austria.

Department of Cardiothoracic Surgery, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.

出版信息

Int J Cardiol Congenit Heart Dis. 2025 May 5;20:100590. doi: 10.1016/j.ijcchd.2025.100590. eCollection 2025 Jun.

DOI:10.1016/j.ijcchd.2025.100590
PMID:40475704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12140042/
Abstract
摘要

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Int J Cardiol Congenit Heart Dis. 2025 May 5;20:100590. doi: 10.1016/j.ijcchd.2025.100590. eCollection 2025 Jun.
2
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本文引用的文献

1
Comprehensive Multiomic Analysis Reveals Metabolic Reprogramming Underlying Human Fontan-Associated Liver Disease.综合多组学分析揭示人类Fontan相关肝病背后的代谢重编程。
J Am Heart Assoc. 2025 Mar 18;14(6):e039201. doi: 10.1161/JAHA.124.039201. Epub 2025 Mar 7.
2
Novel immunologic mechanisms for Fontan-associated liver disease.Fontan 相关肝病的新型免疫机制
Int J Cardiol Congenit Heart Dis. 2024 Nov 27;19:100554. doi: 10.1016/j.ijcchd.2024.100554. eCollection 2025 Mar.
3
Perturbations of tryptophan catabolism via the kynurenine pathway are associated with stage 2 postoperative outcomes in single ventricle heart disease.色氨酸分解代谢通过犬尿氨酸途径的紊乱与单心室心脏病 2 期术后结果相关。
Physiol Rep. 2024 Nov;12(22):e70133. doi: 10.14814/phy2.70133.
4
Gut Dysbiosis in Patients With Fontan Circulation.法洛四联症患者的肠道菌群失调。
J Am Heart Assoc. 2024 Sep 17;13(18):e034538. doi: 10.1161/JAHA.124.034538. Epub 2024 Sep 9.
5
Quantitative plasma proteomic analysis in children after superior cavopulmonary anastomosis with pulmonary arteriovenous malformations.患有肺动静脉畸形的儿童在进行上腔静脉-肺动脉吻合术后的定量血浆蛋白质组学分析。
Pediatr Res. 2025 Feb;97(3):1193-1198. doi: 10.1038/s41390-024-03450-7. Epub 2024 Aug 12.
6
Altered Serum Proteins Suggest Inflammation, Fibrogenesis and Angiogenesis in Adult Patients with a Fontan Circulation.成年 Fontan 循环患者的血清蛋白改变提示炎症、纤维化和血管生成。
Int J Mol Sci. 2024 May 16;25(10):5416. doi: 10.3390/ijms25105416.
7
Single-cell multiomics guided mechanistic understanding of Fontan-associated liver disease.单细胞多组学指导对Fontan相关肝病的机制理解
Sci Transl Med. 2024 Apr 24;16(744):eadk6213. doi: 10.1126/scitranslmed.adk6213.
8
Operational complexities in international clinical trials: a systematic review of challenges and proposed solutions.国际临床试验中的操作复杂性：挑战与解决方案的系统评价。
BMJ Open. 2024 Apr 15;14(4):e077132. doi: 10.1136/bmjopen-2023-077132.
9
Intrahepatic Transcriptomics Differentiate Advanced Fibrosis and Clinical Outcomes in Adults With Fontan Circulation.肝内转录组学可区分 Fontan 循环成人的晚期纤维化和临床结局。
J Am Coll Cardiol. 2024 Feb 20;83(7):726-738. doi: 10.1016/j.jacc.2023.12.005.
10
Elevated oxidative stress in patients with congenital heart disease and the effect of cyanosis: a meta-analysis.先天性心脏病患者氧化应激水平升高与发绀的关系：一项荟萃分析。
Free Radic Res. 2023 May-Jun;57(6-12):470-486. doi: 10.1080/10715762.2023.2284639. Epub 2023 Dec 26.