Monteleone Alessio Maria, Carfagno Marco, Meule Adrian, Naab Silke, Cascino Giammarco, Voderholzer Ulrich, Kolar David R
Department of Psychiatry, University of Campania Luigi Vanvitelli, Naples, Italy.
Department of Psychology, University of Regensburg, Regensburg, Germany.
Int J Eat Disord. 2025 Sep;58(9):1769-1776. doi: 10.1002/eat.24484. Epub 2025 Jun 6.
Although childhood maltreatment, especially emotional abuse, is strongly linked to the psychopathology of anorexia nervosa (AN), the impact of such a traumatic experience on treatment outcome is not clear. This study aimed to explore how emotional abuse affects change in psychopathology during treatment.
Adolescents with AN (n = 331) completed the Childhood Trauma Questionnaire at admission to inpatient treatment and the Eating Disorder Inventory-2, Patient Health Questionnaire-9, Patient Health Questionnaire-15, and Generalized Anxiety Disorder-7 both at admission and at discharge. Relationships of emotional abuse with body mass index (BMI) and questionnaire scores at admission and at discharge were examined with percentage bend correlation coefficients. Changes in BMI and questionnaire scores from admission to discharge and whether these changes were moderated by emotional abuse were tested with robust mixed models.
Higher emotional abuse scores related to higher eating disorder, depressive, anxiety, and somatic symptoms but not to BMI at admission and at discharge. BMI increased and eating disorder, depressive, anxiety, and somatic symptoms decreased from admission to discharge but these changes were not moderated by emotional abuse scores.
Emotional abuse did not affect treatment response during hospitalization for AN, but it was associated with heightened eating and general psychological symptom severity at both hospital admission and discharge. Clinicians are advised to investigate a history of emotional abuse in adolescents with AN and to consider emotional abuse not as a predictor of treatment resistance, but as a psychological scar that persists regardless of symptom severity.
尽管童年期虐待,尤其是情感虐待,与神经性厌食症(AN)的精神病理学密切相关,但这种创伤经历对治疗结果的影响尚不清楚。本研究旨在探讨情感虐待如何影响治疗期间精神病理学的变化。
患有AN的青少年(n = 331)在住院治疗入院时完成儿童创伤问卷,并在入院时和出院时完成饮食失调量表-2、患者健康问卷-9、患者健康问卷-15和广泛性焦虑症量表-7。采用百分比弯曲相关系数检验情感虐待与入院时和出院时体重指数(BMI)及问卷得分之间的关系。使用稳健混合模型测试从入院到出院时BMI和问卷得分的变化,以及这些变化是否受情感虐待的调节。
较高的情感虐待得分与较高的饮食失调、抑郁、焦虑和躯体症状相关,但与入院时和出院时的BMI无关。从入院到出院,BMI增加,饮食失调、抑郁、焦虑和躯体症状减少,但这些变化不受情感虐待得分的调节。
情感虐待在AN住院治疗期间不影响治疗反应,但在入院和出院时均与饮食及一般心理症状严重程度增加有关。建议临床医生调查患有AN的青少年的情感虐待史,并将情感虐待视为一种无论症状严重程度如何都会持续存在的心理创伤,而非治疗抵抗的预测因素。