Benedittis Giuseppe De, Gonda Federico De
Pain Research and Treatment Unit, Institute of Neurosurgery, University of Milan, 20100 MilanItaly.
Pain. 1985 Aug;22(4):375-384. doi: 10.1016/0304-3959(85)90043-0.
At EEG power spectrum analysis, chronic pain patients showed less alpha asymmetry than normal subjects during resting conditions, independently of the aetiology of pain. This 'quasi-symmetry' remained substantially unchanged across discrete task conditions differently from normal subjects showing left hemisphere activation during verbal-mathematic tasks and right hemisphere activation during visuo-spatial tasks. When descriptive diagnosis was considered as related to alpha asymmetry, significant differences were found between 'somatogenic' and 'psychogenic' pain patients. Specifically, somatogenic pain patients conformed to normal subjects, whereas psychogenic pain patients exhibited a trend towards a reduced left hemisphere dominance or a relative right hemisphere activation during both experimental conditions. These EEG findings seem congruent with a more frequent lateralization of psychogenic pain on the left side of the body.
在脑电图功率谱分析中，慢性疼痛患者在静息状态下表现出的α波不对称性比正常受试者少，与疼痛的病因无关。与正常受试者不同，正常受试者在言语-数学任务中表现为左半球激活，在视觉-空间任务中表现为右半球激活，而这种“准对称性”在不同的离散任务条件下基本保持不变。当将描述性诊断与α波不对称性相关联时，发现“躯体性”和“心因性”疼痛患者之间存在显著差异。具体而言，躯体性疼痛患者与正常受试者一致，而心因性疼痛患者在两种实验条件下均表现出左半球优势减弱或相对右半球激活的趋势。这些脑电图结果似乎与心因性疼痛在身体左侧更频繁的偏侧化相一致。
