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[类风湿关节炎的肺部表现,SARS-CoV-2大流行期间的综述]

[Pulmonary manifestations of rheumatoid arthritis, a review in SARS-CoV-2 pandemia].

作者信息

Orozco B Juan David, Imbachí S Alex Jhonier, Ospina Ana Isabel

机构信息

Departamento de Medicina Interna, Facultad de Medicina, Universidad del Cauca, Hospital Universitario San José, Popayán, Colombia.

Servicio de Reumatología, Departamento de Medicina Interna, Facultad de Medicina, Universidad del Cauca, Hospital Universitario San José, Popayán, Colombia.

出版信息

Rev Colomb Reumatol. 2022 Jun;29:S56-S65. doi: 10.1016/j.rcreu.2020.12.005. Epub 2021 Mar 5.

Abstract

Rheumatoid arthritis (RA) is one of the most frequent chronic autoimmune pathologies. It's prevalence varies from 0.5 to 1%, with a primary involvement at the joint, generating disability due to deformities secondary to persistent inflammation. Considering the high impact on the quality of life of those who suffer it, added to the high cost of therapeutic interventions, it becomes imperative for health personnel to join forces to promote early diagnosis and recognize potential complications, in order to impact positively on clinical outcomes. Around 50% of patients with RA may have extra-articular involvement, the lung being one of the most affected organs. In times of SARS-CoV-2 pandemic, it's necessary to remember the types of lung involvement in patients with RA and take into account the susceptibility of these patients to infectious conditions that can generate great morbidity and mortality.

摘要

类风湿性关节炎(RA)是最常见的慢性自身免疫性疾病之一。其患病率在0.5%至1%之间,主要累及关节,由于持续性炎症继发的畸形而导致残疾。考虑到该病对患者生活质量的严重影响,再加上治疗干预成本高昂,卫生人员必须齐心协力促进早期诊断并识别潜在并发症,以便对临床结果产生积极影响。约50%的类风湿性关节炎患者可能有关节外受累情况,肺部是受影响最严重的器官之一。在新冠病毒大流行时期,有必要牢记类风湿性关节炎患者肺部受累的类型,并考虑这些患者对可能导致高发病率和死亡率的感染性疾病的易感性。

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本文引用的文献

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Autoimmunity as the comet tail of COVID-19 pandemic.自身免疫作为新冠疫情的“彗尾”。
World J Clin Cases. 2020 Sep 6;8(17):3621-3644. doi: 10.12998/wjcc.v8.i17.3621.
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Managing rheumatoid arthritis during COVID-19.COVID-19 期间类风湿关节炎的管理。
Clin Rheumatol. 2020 Nov;39(11):3237-3244. doi: 10.1007/s10067-020-05358-z. Epub 2020 Sep 6.
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Clinical features of rheumatic patients infected with COVID-19 in Wuhan, China.中国武汉风湿患者感染 COVID-19 的临床特征。
Ann Rheum Dis. 2020 Aug;79(8):1007-1013. doi: 10.1136/annrheumdis-2020-217627. Epub 2020 May 22.

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