Turner J D, Milhorn H T
Postgrad Med. 1985 Oct;78(5):151-2, 154. doi: 10.1080/00325481.1985.11699159.
Sickle cell trait must be included in the differential diagnosis of hematuria in black patients. Therefore, diagnostic workup should include hemoglobin electrophoresis, urine culture, coagulation studies, intravenous pyelography, cystoscopy, renal ultrasonography, and renal arteriography. If the patient is found to have hemoglobin AS and no other abnormality, initial therapy consists of bed rest and intravenous fluids, with transfusion of red cells if needed. Intravenous epsilon-aminocaproic acid (EACA) has been used effectively to reverse hematuria in patients who do not respond to conservative management. In the case reported here, gross hematuria in a 24-year-old black woman resolved with use of EACA therapy.
镰状细胞性状必须纳入黑人患者血尿的鉴别诊断中。因此，诊断检查应包括血红蛋白电泳、尿培养、凝血研究、静脉肾盂造影、膀胱镜检查、肾脏超声检查和肾动脉造影。如果患者被发现有血红蛋白AS且无其他异常，初始治疗包括卧床休息和静脉补液，必要时输注红细胞。静脉注射ε-氨基己酸（EACA）已被有效用于逆转对保守治疗无反应患者的血尿。在本文报道的病例中，一名24岁黑人女性的肉眼血尿通过使用EACA治疗得以缓解。
