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[竞争性皮质素结合法在皮质醇增多症中测定皮质类固醇水平的诊断信息价值]

[Diagnostic informative value of the method of competitive transcortin binding for determining corticosteroid levels in hypercorticism].

作者信息

Buniatian A F, Mel'nichenko G A, Ignatenko L L

出版信息

Probl Endokrinol (Mosk). 1985 Jul-Aug;31(4):24-7.

PMID:4048092
Abstract

The level of nonmetabolized forms of the corticosteroids hydrocortisone and corticosterone in the blood and urine were determined in 3 groups of patients: with the Icenko-Cushing disease and syndrome and neuroendocrine form of the hypothalamic syndrome. The determination of the level of these hormones, a study of their circadian rhythm by the method of concurrent protein binding have shown that these indices are rather informative and can be recommended as diagnostic and differential criteria for the evaluation of the hypothalamo-hypophyseal-adrenal system.

摘要

对三组患者血液和尿液中皮质类固醇氢化可的松和皮质酮的非代谢形式水平进行了测定

分别为患有伊钦科-库欣病和综合征以及下丘脑综合征神经内分泌形式的患者。对这些激素水平的测定以及通过同时蛋白质结合法对其昼夜节律的研究表明,这些指标具有相当的信息量,可作为评估下丘脑-垂体-肾上腺系统的诊断和鉴别标准推荐使用。

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