Rahlf G, Wilbert L, Lankisch P G, Hüttemann U
Acta Hepatogastroenterol (Stuttg). 1977 Apr;24(2):110-5.
An investigation of the formal patho-genesis of the so-called intramural esophagus diverticulosis is carried out on a case confirmed by autopsy. The roentgenological diagnosis corresponded morphologically with a proliferation of sub-mucous esophagus glands and a dilatation of their outlets, a portion of which displayed platelet epithelial metaplasia. Diverticle formation is feigned by widening, predominantly of the outlets, which could be traced into the muscular wall layers. In the present case esophagitis with attendant inflammation along the outlets lead to fistula formation into the anterior mediastinum with attendant mediastinitis. Aspirations were due to constrictions of the esophagus lumen. The patient came to exitus as a result of purulent abscessing aspiration pneumonia complicated by pulmonary artery emboli.
对一例经尸检证实的所谓壁内食管憩室病的正式发病机制进行了研究。X线诊断在形态学上与食管粘膜下腺体增生及其排泄口扩张相符,其中一部分显示血小板上皮化生。憩室形成是由于排泄口(主要是排泄口)增宽所致,排泄口可延伸至肌层。在本病例中,食管炎及排泄口周围的伴随炎症导致形成通向纵隔前部的瘘管,并伴有纵隔炎。误吸是由于食管腔狭窄所致。患者因脓性脓肿性误吸性肺炎并发肺动脉栓塞而死亡。