Pandeya S N, Srivastava V
Pharmacol Res Commun. 1985 Aug;17(8):699-709. doi: 10.1016/0031-6989(85)90087-6.
A series of S-arylformamidino-N-(alkyl/arylisothiourea) Cyclicamino dihydrochlorides were synthesised and screened for their hypoglycemic activity in normal as well as alloxanized diabetic rats. Some of the compounds (Id, Ie, Ih-1) showed more than 30% lowering of blood sugar level of Albino rats.
合成了一系列S-芳基甲脒基-N-（烷基/芳基异硫脲）环氨基二盐酸盐，并在正常大鼠和四氧嘧啶诱导的糖尿病大鼠中筛选其降血糖活性。一些化合物（Id、Ie、Ih-1）使白化大鼠的血糖水平降低了30%以上。
