Sachs B
Psychiatr Neurol Med Psychol (Leipz). 1985 Jul;37(7):416-20.
Over a period of eight years, 16 patients from a non-selected number of patients in a neuropsychiatric special hospital were diagnosed to suffer from neurolues not known so far. Apart from the classical clinical pictures (PP and T. d.) meningovascular courses of disease with apoplectiform onset have been dominant since 1980. The patients concerned were nearly exclusively younger male adolescents. The decline in the classical development of neurolues in favour of meningovascular and atypical clinical pictures makes clinical diagnosis more difficult and requires routine application of standardized specific and serological tests in clinical practice.
在八年时间里,一家神经精神病专科医院从众多未被挑选的患者中诊断出16例此前未知的神经梅毒患者。自1980年以来,除了典型的临床表现(麻痹性痴呆和梅毒性轻瘫)外,以卒中样起病的脑膜血管型病程一直占主导。相关患者几乎全是年轻男性青少年。神经梅毒经典病程的减少,转而出现脑膜血管型和非典型临床表现,这使得临床诊断更加困难,在临床实践中需要常规应用标准化的特异性和血清学检测。