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Efficacy of Landiolol for Treatment of Sepsis-Related Tachyarrhythmia: Lost in Translation.

作者信息

Chalkias Athanasios, Katsifa Konstantina, Prekates Athanasios, Tselioti Paraskevi

机构信息

Institute for Translational Medicine and Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

Outcomes Research Consortium, Houston, TX, USA.

出版信息

Am J Cardiovasc Drugs. 2025 Jun 8. doi: 10.1007/s40256-025-00736-x.

DOI:10.1007/s40256-025-00736-x
PMID:40483660
Abstract
摘要

相似文献

1
Efficacy of Landiolol for Treatment of Sepsis-Related Tachyarrhythmia: Lost in Translation.兰地洛尔治疗脓毒症相关性快速心律失常的疗效:翻译之失。
Am J Cardiovasc Drugs. 2025 Jun 8. doi: 10.1007/s40256-025-00736-x.
2
Efficacy and Safety of Landiolol in the Treatment of Tachycardia in Patients With Sepsis and Septic Shock: A Systematic Review and Meta-Analysis.兰地洛尔治疗脓毒症和脓毒性休克患者心动过速的疗效与安全性:一项系统评价和Meta分析
Cureus. 2025 Jul 15;17(7):e88004. doi: 10.7759/cureus.88004. eCollection 2025 Jul.
3
Impact of patient characteristics on the efficacy and safety of landiolol in patients with sepsis-related tachyarrhythmia: Subanalysis of the J-Land 3S randomised controlled study.患者特征对兰地洛尔治疗脓毒症相关快速性心律失常疗效和安全性的影响:J-Land 3S随机对照研究的亚组分析
EClinicalMedicine. 2020 Oct 13;28:100571. doi: 10.1016/j.eclinm.2020.100571. eCollection 2020 Nov.
4
Efficacy and safety of landiolol, an ultra-short-acting β1-selective antagonist, for treatment of sepsis-related tachyarrhythmia (J-Land 3S): a multicentre, open-label, randomised controlled trial.兰地洛尔治疗脓毒症相关快速性心律失常的疗效和安全性(J-Land 3S):一项多中心、开放标签、随机对照试验。
Lancet Respir Med. 2020 Sep;8(9):863-872. doi: 10.1016/S2213-2600(20)30037-0. Epub 2020 Mar 31.
5
[The application of landiolol in the cardiovascular and intensive care].兰地洛尔在心血管及重症监护中的应用
Orv Hetil. 2022 Jan 9;163(2):53-62. doi: 10.1556/650.2022.32347.
6
The efficacy of landiolol for suppressing the hyperdynamic response following laryngoscopy and tracheal intubation: a systematic review.兰地洛尔抑制喉镜检查和气管插管后高动力反应的疗效:一项系统评价。
Anaesth Intensive Care. 2009 Nov;37(6):893-902. doi: 10.1177/0310057X0903700621.
7
Effects of landiolol on refractory tachyarrhythmia after total cavopulmonary connection: a retrospective, observational, cohort study.兰地洛尔对全腔静脉肺动脉连接术后难治性快速心律失常的影响:一项回顾性、观察性队列研究。
J Anesth. 2016 Apr;30(2):331-6. doi: 10.1007/s00540-015-2119-4. Epub 2015 Dec 23.
8
Safety and Efficacy of Landiolol Hydrochloride in Children with Tachyarrhythmia of Various Etiologies.盐酸兰地洛尔在各种病因引起的儿童快速性心律失常中的安全性和疗效。
Pediatr Cardiol. 2021 Dec;42(8):1700-1705. doi: 10.1007/s00246-021-02653-7. Epub 2021 Jun 7.
9
Landiolol is effective and safe in paediatric supraventricular tachycardia: evidence from a European prospective multicentre open-label phase III study (LANDI-PED).兰地洛尔治疗小儿室上性心动过速有效且安全:来自一项欧洲前瞻性多中心开放标签III期研究(LANDI-PED)的证据。
Europace. 2025 Feb 5;27(2). doi: 10.1093/europace/euaf025.
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Landiolol bolus application for tachycardic dysrhythmia in the prehospital EMS setting - An observational study of a novel concept.院前急救医疗服务环境下用于快速性心律失常的单次静脉注射兰地洛尔——一项关于新概念的观察性研究
Scand J Trauma Resusc Emerg Med. 2025 Jul 6;33(1):119. doi: 10.1186/s13049-025-01438-8.

本文引用的文献

1
In vivo effects of cardiomyocyte-specific β-1 blockade on afterload- and frequency-dependent cardiac performance.心肌细胞特异性β-1受体阻断对后负荷和频率依赖性心脏功能的体内效应。
Am J Physiol Heart Circ Physiol. 2025 Mar 1;328(3):H543-H549. doi: 10.1152/ajpheart.00795.2024. Epub 2025 Jan 31.
2
The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Randomised Study.超选择性β1受体拮抗作用对接受去甲肾上腺素治疗的脓毒性休克患者代谢和细胞因子谱的影响:来自STRESS-L随机研究的一项子研究。
Intensive Care Med Exp. 2025 Jan 22;13(1):9. doi: 10.1186/s40635-024-00708-6.
3
Landiolol for heart rate control in patients with septic shock and persistent tachycardia. A multicenter randomized clinical trial (Landi-SEP).
兰地洛尔用于感染性休克和持续性心动过速患者的心率控制。一项多中心随机临床试验(Landi-SEP)。
Intensive Care Med. 2024 Oct;50(10):1622-1634. doi: 10.1007/s00134-024-07587-1. Epub 2024 Sep 19.
4
Mortality in Patients With Sepsis Treated With Esmolol or Landiolol: A Systematic Review and Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis.使用艾司洛尔或兰地洛尔治疗的脓毒症患者的死亡率:一项采用序贯试验分析的随机对照试验的系统评价和荟萃分析。
Chest. 2025 Jan;167(1):121-138. doi: 10.1016/j.chest.2024.08.020. Epub 2024 Aug 26.
5
Landiolol and Organ Failure in Patients With Septic Shock: The STRESS-L Randomized Clinical Trial.地佐辛和脓毒性休克患者的器官衰竭:STRESS-L 随机临床试验。
JAMA. 2023 Nov 7;330(17):1641-1652. doi: 10.1001/jama.2023.20134.
6
Mechanisms of landiolol-mediated positive inotropy in critical care settings.Landiolol 在重症监护环境中发挥正性肌力作用的机制。
Eur J Clin Pharmacol. 2023 Dec;79(12):1607-1612. doi: 10.1007/s00228-023-03584-3. Epub 2023 Oct 21.
7
Beta-blocker treatment in the critically ill: a systematic review and meta-analysis.危重症患者的β受体阻滞剂治疗:系统评价和荟萃分析。
Ann Med. 2022 Dec;54(1):1994-2010. doi: 10.1080/07853890.2022.2098376.
8
Effect of landiolol in patients with tachyarrhythmias and acute decompensated heart failure (ADHF): a case series.Landiolol 在伴有快速性心律失常和急性失代偿性心力衰竭(ADHF)患者中的作用:病例系列研究。
ESC Heart Fail. 2022 Feb;9(1):766-770. doi: 10.1002/ehf2.13763. Epub 2021 Dec 27.
9
Impact of baseline beta-blocker use on inotrope response and clinical outcomes in cardiogenic shock: a subgroup analysis of the DOREMI trial.基线使用β受体阻滞剂对心源性休克儿茶酚胺反应和临床结局的影响:DOREMI 试验的亚组分析。
Crit Care. 2021 Aug 10;25(1):289. doi: 10.1186/s13054-021-03706-2.
10
Systolic-dicrotic notch pressure difference can identify tachycardic patients with septic shock at risk of cardiovascular decompensation following pharmacological heart rate reduction.收缩期双波切迹压力差可识别心动过速性脓毒性休克患者,此类患者在接受药物降心率治疗后有发生心血管失代偿的风险。
Br J Anaesth. 2020 Dec;125(6):1018-1024. doi: 10.1016/j.bja.2020.05.058. Epub 2020 Jul 18.