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术前营养障碍对全髋关节置换术后早期身体功能的影响。

Impact of preoperative nutritional impairment on physical function early after total hip arthroplasty.

作者信息

Fujita Tsutomu, Hamai Satoshi, Konishi Toshimi, Okazawa Kazuya, Nasu Yuki, Hara Daisuke, Kawahara Shinya, Yamaguchi Ryosuke, Sato Taishi, Utsunomiya Ken, Motomura Goro, Kawaguchi Kenichi, Nakashima Yasuharu

机构信息

Department of Rehabilitation, Kyushu University Hospital, Fukuoka, Japan.

Department of Artificial Joint and Biomaterials, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan.

出版信息

Bone Jt Open. 2025 Jun 9;6(6):667-676. doi: 10.1302/2633-1462.66.BJO-2024-0261.R1.

Abstract

AIMS

To investigate whether preoperative nutritional status, assessed by the Geriatric Nutritional Risk Index (GNRI), predicts postoperative physical function following total hip arthroplasty (THA).

METHODS

A total of 681 patients (87 males, 594 females; mean age 65.3 years (SD 10.2)) who underwent unilateral primary THA for hip osteoarthritis were included. GNRI was calculated from preoperative serum albumin levels, categorizing patients into three groups: normal nutrition (GNRI ≥ 98), moderate malnutrition (92 ≤ GNRI < 98), and severe malnutrition (GNRI < 92). Physical function, including hip joint range of motion, muscle strength (hip abduction, knee extension), leg length difference, and comfortable walking speed, was assessed preoperatively and at discharge. Group comparisons were made based on GNRI scores, and a multiple regression analysis was conducted using preoperative muscle strength ratio and postoperative comfortable walking speed as outcome variables. Receiver operating characteristic curves determined a preoperative GNRI cut-off value for achieving a postoperative comfortable walking speed of 0.8 m/s.

RESULTS

The moderate and severe malnutrition comprised 68 (10%) and 19 (3%) patients with GNRI: 92 ≤ GNRI < 98 and < 92, respectively, whereas 594 (87%) were in the normal nutrition (GNRI ≥ 98). Patients with malnutrition demonstrated significantly lower preoperative muscle strength and pre- and postoperative muscle strength ratios (p < 0.001). Preoperative GNRI was a significant predictor of hip abductor muscle strength (p = 0.031) and postoperative comfortable walking speed (p < 0.001). The determined preoperative GNRI cut-off score for achieving a postoperative comfortable walking speed of 0.8 m/s was 98.

CONCLUSION

Preoperative GNRI serves as a valuable indicator for improving postoperative muscle strength and comfortable walking speed.

摘要

目的

探讨通过老年营养风险指数(GNRI)评估的术前营养状况是否能预测全髋关节置换术(THA)后的术后身体功能。

方法

纳入681例因髋关节骨关节炎接受单侧初次THA的患者(87例男性,594例女性;平均年龄65.3岁(标准差10.2))。根据术前血清白蛋白水平计算GNRI,将患者分为三组:营养正常(GNRI≥98)、中度营养不良(92≤GNRI<98)和重度营养不良(GNRI<92)。术前和出院时评估身体功能,包括髋关节活动范围、肌肉力量(髋关节外展、膝关节伸展)、腿长差异和舒适步行速度。根据GNRI评分进行组间比较,并以术前肌肉力量比值和术后舒适步行速度作为结果变量进行多元回归分析。通过绘制受试者工作特征曲线确定达到术后舒适步行速度0.8 m/s的术前GNRI临界值。

结果

中度和重度营养不良患者分别有68例(10%)和19例(3%),GNRI分别为92≤GNRI<98和<92,而594例(87%)为营养正常(GNRI≥98)。营养不良患者术前肌肉力量以及术前和术后肌肉力量比值均显著较低(p<0.001)。术前GNRI是髋关节外展肌力量(p=0.031)和术后舒适步行速度(p<0.001)的显著预测指标。确定达到术后舒适步行速度0.8 m/s的术前GNRI临界评分为98。

结论

术前GNRI是改善术后肌肉力量和舒适步行速度的有价值指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dba9/12145927/17aac17852f1/BJO-2024-0261.R1-galleyfig1.jpg

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