Mulukutla Raghava D, Yelamarthy Phani Krishna Karthik, Krishna Narayan Thiruvoipati Venkata, Kathare Ambadas, Yeldandi Vijay V
Department of Spine Surgery, Udai Omni Hospital, Hyderabad, Telangana, India.
Division of Infectious Diseases, University of Illinois, Chicago, Illinois, United States.
Asian J Neurosurg. 2025 Feb 10;20(2):383-386. doi: 10.1055/s-0045-1802624. eCollection 2025 Jun.
We present a case of hospital-acquired spondylodiscitis following lumbar spine surgery. The objective is to highlight the need for a high index of suspicion for rare fungal pathogens as causative organisms in postoperative spinal infections. A 39-year-old female underwent posterior decompression, stabilization, and interbody fusion at L4-5. Six weeks post-surgery she developed fever, back pain, and right leg pain. A diagnosis of postoperative spinal infection was made. On exploration and debridement of the wound, the fungal cultures grew positive for . She was treated with voriconazole for 6 months. Following debridement and antifungal therapy, symptoms and inflammatory markers subsided over a period of time. There was no recurrence of infection till the last follow-up at three and half years. To the best of our knowledge, this is the only case report of an spondylodiscitis following lumbar spine surgery. The possibility of fungal infection should be considered in elderly and immune-compromised patients. In our institution, all postoperative spinal infections, irrespective of age and comorbidities, are subjected to microbiological cultures including fungal cultures and sensitivities. Thorough debridement, involvement of infection control specialists, and use of long-term antifungal therapy help resolve these infections.
我们报告一例腰椎手术后医院获得性脊椎椎间盘炎病例。目的是强调对于术后脊柱感染中作为致病生物的罕见真菌病原体,需要高度怀疑。一名39岁女性在L4 - 5节段接受了后路减压、固定和椎间融合手术。术后六周,她出现发热、背痛和右腿疼痛。诊断为术后脊柱感染。在对伤口进行探查和清创时,真菌培养显示 呈阳性。她接受了伏立康唑治疗6个月。经过清创和抗真菌治疗,症状和炎症指标在一段时间内消退。直到三年半的最后一次随访,感染没有复发。据我们所知,这是腰椎手术后 脊椎椎间盘炎的唯一病例报告。对于老年和免疫功能低下的患者,应考虑真菌感染的可能性。在我们机构,所有术后脊柱感染,无论年龄和合并症如何,都要进行包括真菌培养和药敏试验在内的微生物培养。彻底清创、感染控制专家的参与以及长期抗真菌治疗有助于解决这些感染。