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一项针对2型糖尿病患者的为期两年的结构化糖尿病健康教育计划在疾病相关血清标志物方面的有效性。

Effectiveness of a Structured 2-Year Diabetes Health Education Program of Patients with Type 2 Diabetes Mellitus in Disease-Related Serum Markers.

作者信息

Hsieh Yu-Shan, Lo Chin-Lan, Lin Yan-Yu

机构信息

School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei City, Taiwan.

Department of Research, Taipei Medical University Hospital, Taipei City, Taiwan.

出版信息

Diabetes Metab Syndr Obes. 2025 Jun 4;18:1849-1858. doi: 10.2147/DMSO.S519747. eCollection 2025.

Abstract

INTRODUCTION

Previous studies on the impact of diabetes education on disease management have shown that different educational approaches yield varying degrees of effectiveness across different populations. Adopting face-to-face education with long-term follow-up not only allows for monitoring changes in numerical values but also facilitates the observation of patients' learning status.

METHODS

This study investigates the impact of a two-year structured Diabetes Health Education (DHE) program on disease-related serum markers in patients with type 2 diabetes mellitus (T2DM). A five-year observational cohort study with retrospective analysis was conducted, involving 1,080 participants who completed the DHE program and 192 non-participants.

RESULTS

The DHE program included regular educational sessions every three months, covering topics such as blood glucose management, lipid profiles, and healthy lifestyle practices. Results demonstrated significant improvements among DHE participants: HbA1c levels decreased by 37%, fasting glucose by 4%, total cholesterol by 7%, LDL cholesterol by 13%, and triglycerides by 20%, with HDL cholesterol increasing by 3%. Body weight and diastolic blood pressure (DBP) also showed reductions of 4% and 3%, respectively, while systolic blood pressure (SBP) exhibited no significant changes. The improvements in lipid profiles were evident within six months, whereas glycemic markers required at least 1.5 years to achieve significance.

CONCLUSION

These results suggest that a structured DHE program significantly improves glycemic control, lipid profile, and other metabolic-related markers in patients with T2DM. Notably, HbA1c and fasting glucose levels significantly improved after 1.5 years of consistent DHE participation, highlighting the importance of long-term engagement for glycemic benefits.

摘要

引言

先前关于糖尿病教育对疾病管理影响的研究表明,不同的教育方法在不同人群中产生的效果程度各异。采用长期随访的面对面教育不仅能够监测数值变化,还便于观察患者的学习状态。

方法

本研究调查了一项为期两年的结构化糖尿病健康教育(DHE)计划对2型糖尿病(T2DM)患者疾病相关血清标志物的影响。进行了一项为期五年的观察性队列研究并进行回顾性分析,涉及1080名完成DHE计划的参与者和192名未参与者。

结果

DHE计划包括每三个月定期开展教育课程,涵盖血糖管理、血脂水平和健康生活方式等主题。结果显示,DHE参与者有显著改善:糖化血红蛋白(HbA1c)水平下降37%,空腹血糖下降4%,总胆固醇下降7%,低密度脂蛋白胆固醇下降13%,甘油三酯下降20%,高密度脂蛋白胆固醇升高3%。体重和舒张压(DBP)也分别下降了4%和3%,而收缩压(SBP)无显著变化。血脂水平在六个月内就有明显改善,而血糖标志物至少需要1.5年才达到显著变化。

结论

这些结果表明,结构化的DHE计划能显著改善T2DM患者的血糖控制、血脂水平和其他代谢相关标志物。值得注意的是,持续参与DHE 1.5年后,HbA1c和空腹血糖水平显著改善,凸显了长期参与对血糖益处的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ad0/12145788/a8f48794a3cf/DMSO-18-1849-g0001.jpg

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