Bergner R K, Bergner A
Am Fam Physician. 1977 May;15(5):141-8.
Oral administration of xanthine compounds represents the first line of therapy in most patients with asthma. Establishment and maintenance of a therapeutic blood level of the medication requires regular dosgae. Oral sympathomimetic agents with predominantly beta-2 adrenergic activity, if tolerated, are often useful adjuncts to xanthine therapy. Sympathomimetic aerosols are not recommended. Cromolyn is often a valuable prophlactic agent. Corticosteroid aerosols may be useful in limiting adrenal suppression when steroids are necessary.
对大多数哮喘患者而言,口服黄嘌呤化合物是一线治疗方法。要建立并维持药物的治疗血药浓度需要规律给药。主要具有β-2肾上腺素能活性的口服拟交感神经药若能耐受,通常是黄嘌呤治疗的有用辅助药物。不推荐使用拟交感神经气雾剂。色甘酸钠通常是一种有价值的预防性药物。当需要使用类固醇时,皮质类固醇气雾剂可能有助于限制肾上腺抑制。