Gao Jiaqi, Zhang Sheng, Han Jun, Yang Jing
Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, CHN.
Proton Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, CHN.
Cureus. 2025 May 9;17(5):e83803. doi: 10.7759/cureus.83803. eCollection 2025 May.
Real-time adaptive motion management is critical for delivering precise stereotactic body radiotherapy (SBRT) to lung tumors while sparing adjacent organs-at-risk. This case report describes the successful application of the CyberKnife Synchrony™ Respiratory Tracking System (Accuray Inc., Sunnyvale, CA, USA) in a patient with early-stage non-small cell lung cancer (NSCLC). A 70-year-old male with an NSCLC lesion in the left upper lobe underwent SBRT with real-time fiducial-free tracking. The total prescribed dose was 48 Gy in four fractions. Post-treatment imaging confirmed local control with no acute toxicity. This report highlights the clinical feasibility of CyberKnife®-based real-time adaptive motion management for lung SBRT. These practical insights are valuable for centers adopting this technology.
实时自适应运动管理对于在保护相邻危险器官的同时向肺部肿瘤提供精确的立体定向体部放射治疗（SBRT）至关重要。本病例报告描述了射波刀同步™呼吸跟踪系统（美国加利福尼亚州森尼韦尔市Accuray公司）在一名早期非小细胞肺癌（NSCLC）患者中的成功应用。一名70岁男性，左上叶有NSCLC病变，接受了无标记实时跟踪的SBRT。总处方剂量为48 Gy，分4次给予。治疗后成像证实局部控制良好，无急性毒性。本报告强调了基于射波刀®的实时自适应运动管理用于肺部SBRT的临床可行性。这些实践见解对采用该技术的中心具有重要价值。
