Fazekas A, Pósch E, Zelles T
Res Exp Med (Berl). 1985;185(4):319-23. doi: 10.1007/BF01851957.
Effects of the local infusion of bradykinin or isoproterenol were studied on the systemic blood pressure, blood flow, and vascular resistance of the submandibular gland before and after indomethacin treatment in cats. Both bradykinin and isoproterenol were shown to potently increase the glandular perfusion rate. The systemic arterial blood pressure fell by about 20% in response to indomethacin. The enhancement of blood flow by bradykinin or isoproterenol was not, however, affected by indomethacin treatment. The present results appear to suggest that the endogenous prostaglandins are not essentially involved in the development of responses produced by bradykinin or isoproterenol in the cat submandibular gland.
研究了在猫身上，吲哚美辛治疗前后，局部输注缓激肽或异丙肾上腺素对颌下腺的全身血压、血流和血管阻力的影响。结果显示，缓激肽和异丙肾上腺素均能显著提高腺体灌注率。吲哚美辛使全身动脉血压下降约20%。然而，缓激肽或异丙肾上腺素对血流的增强作用不受吲哚美辛治疗的影响。目前的结果似乎表明，内源性前列腺素在猫颌下腺中对缓激肽或异丙肾上腺素产生的反应发展过程中并非必不可少。
