2022年在霍拉马巴德沙希德·拉希米医院评估局部晚期管腔A型患者与三阴性患者的复发率：一项横断面研究。
Assessing the recurrence rate in locally advanced Luminal A patients compared to triple-negative patients in Shahid Rahimi Hospital Khorramabad in 2022: a cross-sectional study.
作者信息
Joudaki Mohammad, Khani Parya, Farokhi Simin, Ahmadi Somaghian Shahram, Rahimi Sarah, Beiranvand Mania, Mokhayeri Yaser, Pajouhi Ali
机构信息
Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran.
Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
出版信息
Ann Med Surg (Lond). 2025 May 13;87(6):3123-3127. doi: 10.1097/MS9.0000000000003338. eCollection 2025 Jun.
BACKGROUND
Breast cancer is one of the most common causes of cancer death in women both globally and in Iran. Although medical breakthroughs have improved its prognosis, different characteristics can vary locally, especially in understudied regions. Therefore, the present study was designed and carried out in 2022 to compare the rate of breast cancer recurrence in Luminal A and triple-negative patients referred to the Shahid Rahimi Hospital in Khorramabad from March 2019 to March 2020.
MATERIALS AND METHODS
This study was a descriptive-analytical cross-sectional study designed and conducted on 59 patients diagnosed with Luminal A and triple-negative breast cancer treated at the Shahid Rahimi Hospital from March 2019 to March 2020. In this study, the data collection instrument was a researcher-designed form that included information such as age, history of recurrence, type of cancer, family history of cancer, personal history of cancer, lymph node involvement, hookah use history, smoking history, breastfeeding history, and material status. Finally, after collecting information, data was analyzed using SPSS software version 25.
RESULTS
The average age of the patients in this study was 49.45 ± 6.01 years, and the youngest and oldest patients were 35 and 62 years, respectively. Among the studied patients, 34 individuals (57.63%) had Luminal A cancer, and 25 patients (42.37%) had triple negative cancer. Recurrence was reported in 23 patients (38.98%), and lymph node involvement was reported in 21 patients (35.59%). Moreover, 14 patients (23.73%) were positive for a personal history of cancer, and 22 patients (37.29%) had a family history of cancer. In this study, the relationship between recurrence and type of cancer and involvement of lymph nodes was statistically significant ( < 0.05).
CONCLUSION
The rate of recurrence in patients with Luminal A cancer was higher than in patients with triple-negative cancer, according to the results of the study. More attention and periodic examinations in terms of recurrence in patients with Luminal A cancer were necessary.
背景
乳腺癌是全球及伊朗女性癌症死亡的最常见原因之一。尽管医学突破改善了其预后，但不同特征在局部地区可能存在差异，尤其是在研究较少的地区。因此，本研究于2022年设计并开展，旨在比较2019年3月至2020年3月转诊至霍拉马巴德沙希德拉希米医院的Luminal A型和三阴性乳腺癌患者的复发率。
材料与方法
本研究为描述性分析横断面研究，对2019年3月至2020年3月在沙希德拉希米医院接受治疗的59例诊断为Luminal A型和三阴性乳腺癌的患者进行设计和实施。在本研究中，数据收集工具是研究者设计的表格，包括年龄、复发史、癌症类型、癌症家族史、个人癌症史、淋巴结受累情况、水烟使用史、吸烟史、母乳喂养史和物质状态等信息。最后，收集信息后，使用SPSS 25版软件进行数据分析。
结果
本研究患者的平均年龄为49.45±6.01岁，最年轻和最年长的患者分别为35岁和62岁。在研究的患者中，34例（57.63%）患有Luminal A型癌症，25例（42.37%）患有三阴性癌症。23例（38.98%）报告有复发，21例（35.59%）报告有淋巴结受累。此外，14例（23.73%）有个人癌症史呈阳性，22例（37.29%）有癌症家族史。在本研究中，复发与癌症类型和淋巴结受累之间的关系具有统计学意义（<0.05）。
结论
根据研究结果，Luminal A型癌症患者的复发率高于三阴性癌症患者。有必要对Luminal A型癌症患者的复发给予更多关注并进行定期检查。
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