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皮肤粟粒性淋巴细胞瘤:一例伴有免疫组化结果的病例报告

Cutaneous miliary Lymphocytoma: A Case Report with Immunohistochemical Findings.

作者信息

Torabi Shatila, Davoodi Sima, Izanlu Mostafa, Etesamizade Pouria, Tayebi Meibodi Naser

机构信息

Cutaneous Leishmaniasis Research Center, Department of Dermatology, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Pathology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Iran J Pathol. 2025 Spring;20(2):235-238. doi: 10.30699/iijp.2024.2025080.3287. Epub 2025 Mar 10.

Abstract

Cutaneous pseudolymphomas (PSLs) as lymphocytic infiltrates are benign lesions that clinically and histopathologically mimic lymphomas. Miliarial type lymphocytoma cutis is an uncommon type of pseudolymphoma that is characterized by multiple semi-translucent micropapules on the sun-exposed regions. We present a 61-year-old woman who was admitted to our clinic with diffuse, sand-like, and erythematous micropapules on her face. Microscopic findings revealed nodular lymphoid aggregation, with the germinal center formation consisting of polyclonal lymphoid infiltrate confirmed by Immunohistochemistry (IHC) studies. According to this clinicopathological correlation, the miliarial type pseudolymphoma was confirmed and she was treated with topical corticosteroid ointment with a good response.

摘要

皮肤假性淋巴瘤(PSLs)作为淋巴细胞浸润性病变,是临床上和组织病理学上模仿淋巴瘤的良性病变。粟粒型皮肤淋巴细胞瘤是一种罕见的假性淋巴瘤类型,其特征是在暴露于阳光的区域出现多个半透明微丘疹。我们报告一位61岁女性,因面部弥漫性、沙样、红斑性微丘疹入住我院。显微镜检查发现结节性淋巴样聚集,免疫组织化学(IHC)研究证实生发中心形成由多克隆淋巴细胞浸润组成。根据这种临床病理相关性,确诊为粟粒型假性淋巴瘤,她接受了外用糖皮质激素软膏治疗,反应良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a284/12142020/4fce55f8fe62/ijp-20-235-g001.jpg

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