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研究袖状胃切除术对城市青年人群的影响。

Examining effects of sleeve gastrectomy in an urban youth population.

作者信息

Ditchek L B, Zitsman J, Woo Baidal J, Oberfield S E, Fennoy I

机构信息

Pediatrics, New York Presbyterian-Columbia, NY, NY, United States.

Pediatrics, Mount Sinai Adolescent Health Center, Icahn School of Medicine at Mount Sinai, NY, NY, United States.

出版信息

Obes Pillars. 2025 May 8;15:100179. doi: 10.1016/j.obpill.2025.100179. eCollection 2025 Sep.

Abstract

BACKGROUND

Extensive evidence demonstrates the positive health effects of metabolic and bariatric surgery (MBS) in adolescents, including a reduction in body mass index (BMI) and improvements in cardiometabolic health. However, studies often lack generalizability due to their inclusion of predominately non-Hispanic White and privately insured patients.

METHODS

This retrospective study aims to provide insight into MBS outcomes for an urban youth population.

RESULTS

All groups showed a statistically significant improvement in BMI, HgbA1c, HDL, and triglyceride levels, postoperatively. Postoperative BMI did not differ between Non-Hispanic and Hispanic participants (P = 0.45) or between publicly and privately insured patients (P = 0.52). There was a statistically significantly lower postoperative HgbA1c in non-Hispanic participants compared to Hispanic participants (P = 0.01) and a statistically significantly lower postoperative Systolic blood pressure (SBP) in privately insured patients compared to publicly insured patient (P = 0.02). No other significant differences were detected between privately/publicly insured and Hispanic/non-Hispanic outcomes at 12 months postoperatively.

CONCLUSION

In our urban youth patient population, MBS resulted in significant improvement in BMI across all groups. Notably, there were no statistically significant differences in preoperative characteristics (BMI, HgbA1, LDL, HDL, triglycerides, total cholesterol, SBP or DBP). However, postoperative differences in HgbA1c and SBP were detected between groups. The reasons behind these differences remain unclear, emphasizing the need for further research with greater population variability. This study underscores the importance of increasing generalizability in studies of MBS to fully understand outcomes in underrepresented groups.

摘要

背景

大量证据表明,代谢和减重手术(MBS)对青少年的健康有积极影响,包括降低体重指数(BMI)和改善心脏代谢健康。然而,由于研究主要纳入非西班牙裔白人和有私人保险的患者,这些研究往往缺乏普遍性。

方法

这项回顾性研究旨在深入了解城市青年人群的MBS手术效果。

结果

所有组术后BMI、糖化血红蛋白(HgbA1c)、高密度脂蛋白(HDL)和甘油三酯水平均有统计学意义上的显著改善。非西班牙裔和西班牙裔参与者术后BMI无差异(P = 0.45),公共保险和私人保险患者之间也无差异(P = 0.52)。与西班牙裔参与者相比,非西班牙裔参与者术后糖化血红蛋白水平在统计学上显著更低(P = 0.01),与公共保险患者相比,私人保险患者术后收缩压(SBP)在统计学上显著更低(P = 0.02)。术后12个月,公共/私人保险和西班牙裔/非西班牙裔结果之间未发现其他显著差异。

结论

在我们的城市青年患者群体中,MBS使所有组的BMI都有显著改善。值得注意的是,术前特征(BMI、HgbA1、低密度脂蛋白、高密度脂蛋白、甘油三酯、总胆固醇、收缩压或舒张压)在统计学上没有显著差异。然而,各亚组间糖化血红蛋白和收缩压的术后差异仍被检测到。这些差异背后的原因尚不清楚,这凸显了在人群差异更大的情况下进行进一步研究的必要性。本研究强调了在MBS研究中提高普遍性的重要性,以便全面了解未被充分代表群体的手术效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a2f/12137160/b195944bb7f1/ga1.jpg

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Examining effects of sleeve gastrectomy in an urban youth population.研究袖状胃切除术对城市青年人群的影响。
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