Raymond L, Infante F, Voirol M, Hollenweger V, Zurkirch-Conti M C, Loizeau E
Schweiz Med Wochenschr. 1985 Jul 20;115(29):998-1000.
Habitual food and alcohol intake throughout adult life were assessed by interview in 211 patients suffering of liver cirrhosis and 387 control subjects selected at random from the corresponding general population. In the cirrhotics only the habits prior to clinical disease were taken into account. A significant dose-response relationship between alcohol intake and relative risk of cirrhosis, as well as the protective effect of total caloric intake and of its protein fraction, was demonstrated by logistic regression analysis.
通过访谈评估了211例肝硬化患者以及从相应普通人群中随机选取的387名对照者成年期的习惯性饮食和酒精摄入量。对于肝硬化患者,仅考虑临床疾病出现之前的习惯。逻辑回归分析表明,酒精摄入量与肝硬化相对风险之间存在显著的剂量反应关系,以及总热量摄入及其蛋白质部分的保护作用。