DiBianco John Michael, Daignault-Newton Stephanie, Fernandez Moncaleano Golena, Stockall Eric, Hiller Spencer, Kim Hyung Joon, Pimentel Hector, Wenzler David, Seifman Brian, Kachroo Naveen, Dauw Casey A, Ghani Khurshid R
Department of Urology, University of Florida, Gainesville, Florida.
Department of Urology, University of Michigan, Ann Arbor, Michigan.
J Urol. 2025 Oct;214(4):415-425. doi: 10.1097/JU.0000000000004628. Epub 2025 Jun 9.
AUA guidelines recommend ureteroscopy (URS) or shock wave lithotripsy (SWL) for lower pole (LP) stones ≤ 1 cm, while SWL is second line for stones > 1 to 2 cm. In the era of increasing URS, there are limited data on the modality used and outcomes. We assessed treatment distribution, stone-free rates (SFRs), and unplanned health care.
Using the Michigan Urological Surgery Improvement Collaborative registry, we identified URS and SWL cases for LP stones ≤ 2 cm (2016-2021). We assessed the frequency of patients receiving URS or SWL as a proportion of their LP treatment. A logistic model determined predictive probability of treatment modality. Differences in complete SFRs, postoperative emergency department visits, and hospitalizations were assessed by size (≤1 cm, >1-2 cm), adjusted for patient factors and correlation within practice/provider.
There were 3645 procedures from 35 practices (209 surgeons); 2287 (62.7%) had SWL. Of the stones 80.2% were ≤ 1 cm. There was variation in modality based on practice ( < .001) and surgeon ( < .001). For stones ≤ 1 cm, the SFR was higher for URS (56% vs 39%; < .001). There were no significant differences in SFRs for > 1 to 2 cm stones. Emergency department visits were higher after URS for stones ≤ 1 cm (odds ratio [OR]: 2.95, 95% CI: 1.7-5.0) but not for > 1 to 2 cm stones (OR: 0.97, 95% CI: 0.4-2.2). URS for stones ≤ 1 cm was associated with increased hospitalizations (OR: 4.67, 95% CI: 1.7-12.9) but not for stones > 1 to 2 cm (OR: 0.96, 95% CI: 0.4-2.2).
In Michigan, SWL is the chosen modality for LP stones ≤ 2 cm. For smaller stones, URS was more effective but had greater morbidity. For larger stones, both modalities demonstrated suboptimal efficacy. Our work demonstrates the need for interventions to improve outcomes.
美国泌尿外科学会(AUA)指南推荐,对于直径≤1 cm的下极(LP)结石采用输尿管镜检查(URS)或冲击波碎石术(SWL),而对于直径>1至2 cm的结石,SWL为二线治疗方法。在URS应用日益广泛的时代,关于所采用的治疗方式及其疗效的数据有限。我们评估了治疗分布、无结石率(SFRs)和非计划医疗保健情况。
利用密歇根泌尿外科手术改善协作登记系统,我们确定了2016 - 2021年间直径≤2 cm的LP结石的URS和SWL病例。我们评估了接受URS或SWL治疗的患者频率占其LP结石治疗的比例。采用逻辑模型确定治疗方式的预测概率。根据结石大小(≤1 cm,>1至2 cm)评估完全无结石率、术后急诊就诊次数和住院情况的差异,并对患者因素及医疗机构/医生内部的相关性进行了校正。
来自35家医疗机构(209名外科医生)的3645例手术;其中2287例(62.7%)采用SWL。80.2%的结石直径≤1 cm。治疗方式因医疗机构(<0.001)和外科医生(<0.001)而异。对于直径≤1 cm的结石,URS的无结石率更高(56%对39%;<0.001)。对于直径>1至2 cm的结石,无结石率无显著差异。对于直径≤1 cm的结石,URS术后急诊就诊次数更高(优势比[OR]:2.95,95%置信区间:1.7 - 5.0),但对于直径>1至2 cm的结石则不然(OR:0.97,95%置信区间:0.4 - 2.2)。直径≤1 cm的结石采用URS与住院次数增加相关(OR:4.67,95%置信区间:1.7 - 12.9),但对于直径>1至2 cm的结石则不然(OR:0.96,95%置信区间:0.4 - 2.2)。
在密歇根州,SWL是直径≤2 cm的LP结石的首选治疗方式。对于较小的结石,URS更有效,但发病率更高。对于较大的结石,两种治疗方式的疗效均欠佳。我们的研究表明需要采取干预措施来改善治疗效果。