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输尿管镜检查与冲击波碎石术治疗下极肾结石:外科协作中的治疗差异与结果

Ureteroscopy vs Shock Wave Lithotripsy for Lower Pole Renal Stones: Treatment Variation and Outcomes in a Surgical Collaborative.

作者信息

DiBianco John Michael, Daignault-Newton Stephanie, Fernandez Moncaleano Golena, Stockall Eric, Hiller Spencer, Kim Hyung Joon, Pimentel Hector, Wenzler David, Seifman Brian, Kachroo Naveen, Dauw Casey A, Ghani Khurshid R

机构信息

Department of Urology, University of Florida, Gainesville, Florida.

Department of Urology, University of Michigan, Ann Arbor, Michigan.

出版信息

J Urol. 2025 Oct;214(4):415-425. doi: 10.1097/JU.0000000000004628. Epub 2025 Jun 9.

Abstract

PURPOSE

AUA guidelines recommend ureteroscopy (URS) or shock wave lithotripsy (SWL) for lower pole (LP) stones ≤ 1 cm, while SWL is second line for stones > 1 to 2 cm. In the era of increasing URS, there are limited data on the modality used and outcomes. We assessed treatment distribution, stone-free rates (SFRs), and unplanned health care.

MATERIALS AND METHODS

Using the Michigan Urological Surgery Improvement Collaborative registry, we identified URS and SWL cases for LP stones ≤ 2 cm (2016-2021). We assessed the frequency of patients receiving URS or SWL as a proportion of their LP treatment. A logistic model determined predictive probability of treatment modality. Differences in complete SFRs, postoperative emergency department visits, and hospitalizations were assessed by size (≤1 cm, >1-2 cm), adjusted for patient factors and correlation within practice/provider.

RESULTS

There were 3645 procedures from 35 practices (209 surgeons); 2287 (62.7%) had SWL. Of the stones 80.2% were ≤ 1 cm. There was variation in modality based on practice ( < .001) and surgeon ( < .001). For stones ≤ 1 cm, the SFR was higher for URS (56% vs 39%; < .001). There were no significant differences in SFRs for > 1 to 2 cm stones. Emergency department visits were higher after URS for stones ≤ 1 cm (odds ratio [OR]: 2.95, 95% CI: 1.7-5.0) but not for > 1 to 2 cm stones (OR: 0.97, 95% CI: 0.4-2.2). URS for stones ≤ 1 cm was associated with increased hospitalizations (OR: 4.67, 95% CI: 1.7-12.9) but not for stones > 1 to 2 cm (OR: 0.96, 95% CI: 0.4-2.2).

CONCLUSIONS

In Michigan, SWL is the chosen modality for LP stones ≤ 2 cm. For smaller stones, URS was more effective but had greater morbidity. For larger stones, both modalities demonstrated suboptimal efficacy. Our work demonstrates the need for interventions to improve outcomes.

摘要

目的

美国泌尿外科学会(AUA)指南推荐,对于直径≤1 cm的下极(LP)结石采用输尿管镜检查(URS)或冲击波碎石术(SWL),而对于直径>1至2 cm的结石,SWL为二线治疗方法。在URS应用日益广泛的时代,关于所采用的治疗方式及其疗效的数据有限。我们评估了治疗分布、无结石率(SFRs)和非计划医疗保健情况。

材料与方法

利用密歇根泌尿外科手术改善协作登记系统,我们确定了2016 - 2021年间直径≤2 cm的LP结石的URS和SWL病例。我们评估了接受URS或SWL治疗的患者频率占其LP结石治疗的比例。采用逻辑模型确定治疗方式的预测概率。根据结石大小(≤1 cm,>1至2 cm)评估完全无结石率、术后急诊就诊次数和住院情况的差异,并对患者因素及医疗机构/医生内部的相关性进行了校正。

结果

来自35家医疗机构(209名外科医生)的3645例手术;其中2287例(62.7%)采用SWL。80.2%的结石直径≤1 cm。治疗方式因医疗机构(<0.001)和外科医生(<0.001)而异。对于直径≤1 cm的结石,URS的无结石率更高(56%对39%;<0.001)。对于直径>1至2 cm的结石,无结石率无显著差异。对于直径≤1 cm的结石,URS术后急诊就诊次数更高(优势比[OR]:2.95,95%置信区间:1.7 - 5.0),但对于直径>1至2 cm的结石则不然(OR:0.97,95%置信区间:0.4 - 2.2)。直径≤1 cm的结石采用URS与住院次数增加相关(OR:4.67,95%置信区间:1.7 - 12.9),但对于直径>1至2 cm的结石则不然(OR:0.96,95%置信区间:0.4 - 2.2)。

结论

在密歇根州,SWL是直径≤2 cm的LP结石的首选治疗方式。对于较小的结石,URS更有效,但发病率更高。对于较大的结石,两种治疗方式的疗效均欠佳。我们的研究表明需要采取干预措施来改善治疗效果。

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