Cohen C J
Semin Oncol. 1985 Sep;12(3 Suppl 4):53-6.
A primary consideration for effective management of ovarian cancer is distinguishing patients with advanced bulky disease from those with other stages of disease. It is important to determine whether a tumor is confined to one ovary or is more wide-spread. Surgical management includes removal of both ovaries and tubes, the uterus, omentum, and bulk of the disease. The degree of bulk reduction achieved significantly impacts on survival. Conservation is justified in some cases. Intraperitoneal treatment with platinum-based chemotherapy postsurgery appears to substantially benefit patients with minimal residual disease. In a study comparing two catheter methods, fewer complications were noted with the disposable single-use catheter than with the implanted catheter. Surgical endstaging can definitively identify cured patients. However, it is a difficult procedure and is contraindicated in patients with severe intercurrent illness, previous extensive radiotherapy, and an obliterated peritoneal cavity.
有效管理卵巢癌的一个主要考虑因素是区分患有晚期大块疾病的患者与患有其他疾病阶段的患者。确定肿瘤是局限于一个卵巢还是扩散得更广很重要。手术管理包括切除双侧卵巢和输卵管、子宫、大网膜以及大部分病灶。实现的减瘤程度对生存率有显著影响。在某些情况下，保留是合理的。术后腹腔内使用铂类化疗似乎能使残留疾病最少的患者受益匪浅。在一项比较两种导管方法的研究中，一次性使用导管的并发症比植入式导管少。手术分期可以明确识别治愈的患者。然而，这是一个困难的手术，在患有严重并发疾病、先前接受过广泛放疗以及腹膜腔闭塞的患者中是禁忌的。
