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用于骶骨肿瘤切除术的患者特异性三维重建模型:病例说明

Patient-specific 3D reconstruction models for sacral tumor resection: illustrative cases.

作者信息

Sanker Vivek, Gonzalez-Suarez Aneysis D, Innocenti Niccolo, Cavagnaro Maria Jose, Jeon Ikchan, Zygourakis Corinna, Desai Atman

机构信息

Department of Neurosurgery, Stanford University, Stanford, California.

Department of Neurosurgery, Yeungnam University Hospital, Yeungnam University College of Medicine, Daegu, South Korea.

出版信息

J Neurosurg Case Lessons. 2025 Jun 9;9(23). doi: 10.3171/CASE2522.

DOI:10.3171/CASE2522
PMID:40489946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12147658/
Abstract

BACKGROUND

The surgical methods used to resect sacral tumors are extensive and require maneuvering through complex anatomical systems such as the pelvic organs and sacral nerve roots. These procedures may result in complications and adverse patient outcomes. The technology integrating 3D reconstruction models in the field of spine surgery is rapidly evolving, and these challenging cases present a unique opportunity to leverage this technology's capability for enhanced patient outcomes.

OBSERVATIONS

The authors present two sacral tumor cases diagnosed with synovial cell sarcoma and giant cell osteosarcoma, respectively. Both patients underwent a three-staged en bloc tumor resection assisted by 3D reconstruction models. Postoperative imaging showed a complete tumor resection, and the patients symptomatically improved, with no signs of recurrence on follow-up.

LESSONS

Surgical planning and execution have clearly advanced significantly with the introduction of 3D modeling into spine surgery. Based on the authors' experience, this technology can be used to improve outcomes for complicated spinal tumors with successful results. Although these results are encouraging, extensive studies with larger patient cohorts must be carried out to fully appreciate the technology's advantages across a range of patient demographics and tumor types. https://thejns.org/doi/10.3171/CASE2522.

摘要

背景

用于切除骶骨肿瘤的手术方法范围广泛,需要在诸如盆腔器官和骶神经根等复杂解剖系统中进行操作。这些手术可能会导致并发症和不良的患者预后。脊柱外科领域中整合三维重建模型的技术正在迅速发展,而这些具有挑战性的病例为利用该技术的能力以改善患者预后提供了独特的机会。

观察

作者分别展示了两例被诊断为滑膜细胞肉瘤和巨细胞骨肉瘤的骶骨肿瘤病例。两名患者均在三维重建模型辅助下接受了分三步的整块肿瘤切除术。术后影像学检查显示肿瘤完全切除,患者症状改善,随访时无复发迹象。

经验教训

随着三维建模引入脊柱外科,手术规划和实施显然有了显著进展。根据作者的经验,这项技术可用于改善复杂脊柱肿瘤的治疗效果并取得成功。尽管这些结果令人鼓舞,但必须开展针对更大患者群体的广泛研究,以全面了解该技术在一系列患者人口统计学特征和肿瘤类型中的优势。https://thejns.org/doi/10.3171/CASE2522

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/b5554a23cd8b/CASE2522_figure_5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/490990269304/CASE2522_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/022e00584208/CASE2522_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/e51488221d72/CASE2522_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/f6df079d25cd/CASE2522_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/b5554a23cd8b/CASE2522_figure_5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/490990269304/CASE2522_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/022e00584208/CASE2522_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/e51488221d72/CASE2522_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/f6df079d25cd/CASE2522_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df3f/12147658/b5554a23cd8b/CASE2522_figure_5.jpg

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本文引用的文献

1
Complication Pattern of Sacral Primary Tumor Resection: A Study on the Risk Factors of Surgical Site Infection and Bowel or Bladder Dysfunction and Their Associations with Length of Hospital Stay.骶骨原发性肿瘤切除术的并发症模式:关于手术部位感染、肠道或膀胱功能障碍的危险因素及其与住院时间的关联的研究
Asian Spine J. 2023 Oct;17(5):851-861. doi: 10.31616/asj.2022.0404. Epub 2023 Sep 11.
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Augmented Reality in Spine Surgery: Current State of the Art.脊柱手术中的增强现实技术:当前技术水平
Int J Spine Surg. 2022 Oct;16(S2):S22-S27. doi: 10.14444/8273. Epub 2022 Oct 20.
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Augmented Reality Neuronavigation for En Bloc Resection of Spinal Column Lesions.
增强现实神经导航在整块切除脊柱病变中的应用。
World Neurosurg. 2022 Nov;167:102-110. doi: 10.1016/j.wneu.2022.08.143. Epub 2022 Sep 9.
4
Nerve Root Sparing En Bloc Resection of Sacral Chondrosarcoma: Technical Note and Review of the Literature.神经根保护整块切除骶骨软骨肉瘤:技术说明及文献复习。
Oper Neurosurg (Hagerstown). 2021 Nov 15;21(6):497-506. doi: 10.1093/ons/opab333.
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Demystifying Sacral Masses: A Pictorial Review.骶骨肿物揭秘:图文综述
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Clinical manifestations, classification, and surgical management of sacral tumors and the need for personalized approach to sacrectomy.骶骨肿瘤的临床表现、分类及手术治疗,以及骶骨切除术个性化方法的必要性。
Surg Neurol Int. 2021 May 3;12:209. doi: 10.25259/SNI_133_2021. eCollection 2021.
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Augmented and virtual reality in spine surgery, current applications and future potentials.脊柱手术中的增强现实和虚拟现实:当前应用和未来潜力。
Spine J. 2021 Oct;21(10):1617-1625. doi: 10.1016/j.spinee.2021.03.018. Epub 2021 Mar 25.
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Current state of navigation in spine surgery.脊柱外科手术中的导航现状。
Ann Transl Med. 2021 Jan;9(1):85. doi: 10.21037/atm-20-1335.
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Augmented reality navigation in spine surgery: a systematic review.增强现实导航在脊柱手术中的应用:系统评价。
Acta Neurochir (Wien). 2021 Mar;163(3):843-852. doi: 10.1007/s00701-021-04708-3. Epub 2021 Jan 28.
10
Clinical Accuracy, Technical Precision, and Workflow of the First in Human Use of an Augmented-Reality Head-Mounted Display Stereotactic Navigation System for Spine Surgery.首例人体应用增强现实头戴式显示器立体定向导航系统用于脊柱手术的临床准确性、技术精度和工作流程。
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