Hohn D C, Granelli S G, Burton R W, Hunt T K
Am J Surg. 1977 May;133(5):601-6. doi: 10.1016/0002-9610(77)90019-8.
Human wound fluid contains heat-stable proteins with moderate antibacterial activity against Staphylococcus aureus and Escherichia coli, and different heat-labile proteins with antibacterial activity against E coli. Blood serum also contains heat-labile antibacterial substances, but little heat-stable activity against Staphylococcus aureus. Both blood serum and wound fluid have bacteriostatic activity against S epidermidis, and early growth of Streptococcus fecalis occurs in serum and wound fluids. The concentration or activity of antimicrobial proteins increases during the first week in the fresh wound and then decreases as the wound matures.
人伤口渗出液含有对金黄色葡萄球菌和大肠杆菌具有中等抗菌活性的热稳定蛋白，以及对大肠杆菌具有抗菌活性的不同热不稳定蛋白。血清也含有热不稳定抗菌物质，但对金黄色葡萄球菌的热稳定活性很低。血清和伤口渗出液对表皮葡萄球菌均有抑菌活性，血清和伤口渗出液中粪链球菌可早期生长。新鲜伤口中抗菌蛋白的浓度或活性在第一周内升高，然后随着伤口成熟而降低。
