Miklowitz David J, Weintraub Marc J, Denenny Danielle M, Merranko John A, Hooley Jill M
Department of Psychiatry and Behavioral Sciences, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, 760 Westwood Plaza, Los Angeles, CA 90024-1759, USA.
Department of Psychiatry and Behavioral Sciences, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, 760 Westwood Plaza, Los Angeles, CA 90024-1759, USA.
J Affect Disord. 2025 Nov 15;389:119620. doi: 10.1016/j.jad.2025.119620. Epub 2025 Jun 9.
Levels of expressed emotion (EE) in caregivers are associated with recurrence risk in individuals with mood disorders. In adolescent offspring of parents with mood disorders, we examined the longitudinal associations between parental EE, family conflict and youths' mood states during a trial of family-focused therapy (FFT).
Participants (N = 62; mean 15.7 yrs. ± 1.6) had current depressed mood, mood instability, and a parent with a history of depression or bipolar disorder. Families received 12 sessions of videoconference-based FFT (psychoeducation, communication, and problem-solving) over 18 weeks, with random assignment to one of two mobile apps. Levels of EE based on five-minute speech samples were obtained from parents at pretreatment and every 9 weeks over 27 weeks. At each 9-week interval, independent evaluators rated youths' mood symptoms and adolescents/parents rated family conflict and mood instability.
Levels of EE were stable from baseline to post-treatment in 70.4 % of parents. Over 27 weeks, youth in low-EE families showed greater improvements in depressive symptoms and mood lability compared to those in high-EE families. Parents who were high-EE in one study interval reported higher parent/offspring conflict in the next interval. The association between parental EE and youths' mood symptoms was partially mediated by family conflict. Findings were unaffected by type of mobile app assigned to families.
Despite its prognostic significance, we cannot draw conclusions about the causal role of parental EE in youths' mood fluctuations.
The pathways from parental EE to family conflict and youths' mood fluctuations suggest strategies for early intervention.
Technology Enhanced Family Treatment; https://clinicaltrials.gov/NCT03913013.
照料者的表达性情绪(EE)水平与情绪障碍患者的复发风险相关。在患有情绪障碍的父母的青少年子女中,我们在一项以家庭为中心的治疗(FFT)试验中研究了父母的EE、家庭冲突与青少年情绪状态之间的纵向关联。
参与者(N = 62;平均年龄15.7岁±1.6岁)目前有抑郁情绪、情绪不稳定,且父母一方有抑郁或双相情感障碍病史。家庭在18周内接受了12次基于视频会议的FFT(心理教育、沟通和问题解决),并随机分配到两个移动应用程序之一。在治疗前以及27周内每9周从父母那里获取基于5分钟言语样本的EE水平。在每9周的间隔期,独立评估者对青少年的情绪症状进行评分,青少年/父母对家庭冲突和情绪不稳定进行评分。
70.4%的父母的EE水平从基线到治疗后保持稳定。在27周内,与高EE家庭的青少年相比,低EE家庭的青少年在抑郁症状和情绪易变性方面有更大改善。在一个研究间隔期内EE高的父母在下一个间隔期报告的亲子冲突更高。父母的EE与青少年情绪症状之间的关联部分由家庭冲突介导。研究结果不受分配给家庭的移动应用程序类型的影响。
尽管其具有预后意义,但我们无法得出关于父母的EE在青少年情绪波动中因果作用的结论。
从父母的EE到家庭冲突和青少年情绪波动的途径提示了早期干预策略。
技术强化家庭治疗;https://clinicaltrials.gov/NCT03913013 。