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比较两种版本的HACOR量表在预测巴西患者无创通气失败方面的临床测量特性。

Comparison of the clinimetric properties of the two versions of the HACOR scale for predicting noninvasive ventilation failure in Brazilian patients.

作者信息

da Silva Matheus Pereira Nunes, Lunardi Adriana Claudia

机构信息

Master and Doctoral Program in Physical Therapy, Universidade Cidade de São Paulo, São Paulo, Brasil.

Physical Therapy Service, Hospital Santa Marcelina de Itaquera, São Paulo, Brasil.

出版信息

Acute Crit Care. 2025 May;40(2):322-329. doi: 10.4266/acc.000175. Epub 2025 May 28.

Abstract

BACKGROUND

Scales that detect noninvasive ventilation (NIV) failure need to have adequate clinimetric properties to be reliable. This study aimed to compare the clinimetric properties of the Heart rate, Acidosis, Consciousness, Oxygenation, Respiratory rate (HACOR) and updated HACOR scales when applied to hypoxemic adult patients undergoing NIV.

METHODS

This prospective study applied the HACOR and updated HACOR scales to hypoxemic patients after one hour of NIV in an emergency department setting. A second application of the scales was performed after ten minutes to assess reliability (intraclass correlation coefficient), measurement error (standard error of measurement and minimum detectable difference), ceiling and floor effects, convergent validity by correlation (Pearson's r) with peripheral oximetry saturation (SpO2), and predictive validity (area under the receiver operating characteristic [ROC] curve) for the outcome of needing invasive mechanical ventilation.

RESULTS

Sixty patients were included in this study (59.45±17.48 years; Simplified Acute Physiology Score III, 56.1±13.95; 30% with respiratory disease and 25% with cardiovascular disease). After 1 hour of NIV, patients had a HACOR score of 3 (interquartile range [IQR], 1.0-5.0) and an updated HACOR score of 5 (IQR, 3.0-8.87). Clinimetric properties were adequate for both versions of the HACOR scale but were superior for the updated version, including predictive validity (ROC [95% CI], 0.78 [0.64-0.91] vs. 0.73 [0.57-0.89]) and the absence of the ceiling effect.

CONCLUSIONS

Both versions of the HACOR scale demonstrated adequate clinimetric properties for predicting NIV failure, with the updated HACOR version showing superior predictive validity and no ceiling effect compared with the original version.

摘要

背景

用于检测无创通气(NIV)失败的量表需要具备足够的临床测量特性才能可靠。本研究旨在比较心率、酸中毒、意识、氧合、呼吸频率(HACOR)量表和更新后的HACOR量表应用于接受NIV的低氧血症成年患者时的临床测量特性。

方法

这项前瞻性研究在急诊科环境中对低氧血症患者进行无创通气1小时后应用HACOR量表和更新后的HACOR量表。10分钟后再次应用这些量表以评估可靠性(组内相关系数)、测量误差(测量标准误差和最小可检测差异)、天花板效应和地板效应、与外周血氧饱和度(SpO2)的相关性(Pearson's r)的收敛效度以及对需要有创机械通气结局的预测效度(受试者工作特征[ROC]曲线下面积)。

结果

本研究纳入了60例患者(年龄59.45±17.48岁;简化急性生理学评分III,56.1±13.95;30%患有呼吸系统疾病,25%患有心血管疾病)。无创通气1小时后,患者的HACOR评分为3(四分位数间距[IQR],1.0 - 5.0),更新后的HACOR评分为5(IQR,3.0 - 8.87)。两种版本的HACOR量表的临床测量特性均足够,但更新版本更优,包括预测效度(ROC[95%CI],0.78[0.64 - 0.91]对0.73[0.57 - 0.89])以及无天花板效应。

结论

两种版本的HACOR量表在预测无创通气失败方面均显示出足够的临床测量特性,与原始版本相比,更新后的HACOR版本显示出更好的预测效度且无天花板效应。

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