Huffman J L, Morse M J, Herr H W, Whitmore W F
Urology. 1985 Oct;26(4 Suppl):47-50.
The use of topical chemotherapy for the treatment of upper urinary tract urothelial tumors and the selection of patients to receive this treatment remain problematic because of the relatively infrequent occurrence of these tumors compared with similar tumors within the bladder. The lack of clinicopathologic information on upper urinary tract urothelial tumors makes pretherapy diagnosis and clinical staging difficult. In addition, there are problems associated with delivery of the agent, and there is not as yet an effective method of surveillance after treatment. Only continued investigation with endoscopic diagnosis and treatment, as well as longitudinal follow-up, will determine methods of patients selection and the optimal use of topical chemotherapy.
与膀胱内的类似肿瘤相比，上尿路尿路上皮肿瘤相对少见，因此使用局部化疗治疗上尿路尿路上皮肿瘤以及选择接受该治疗的患者仍然存在问题。上尿路尿路上皮肿瘤缺乏临床病理信息，使得治疗前诊断和临床分期变得困难。此外，药物递送存在问题，并且治疗后尚未有一种有效的监测方法。只有通过内镜诊断和治疗以及长期随访的持续研究，才能确定患者选择方法和局部化疗的最佳使用方式。
