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全髋关节置换术后结核感染误诊为假性滑液囊肿:一例报告

Misdiagnosis of tuberculous infection as pseudo-bursa cyst after total hip arthroplasty: a case report.

作者信息

Jia Zhen, Chang Zhengqi, Wan Shiyong

机构信息

Department of Orthopedics, 961th Hospital of PLA, Qiqihaer, China.

Department of Orthopedics, 960th Hospital of PLA, Jinan, China.

出版信息

Front Surg. 2025 May 27;12:1612055. doi: 10.3389/fsurg.2025.1612055. eCollection 2025.

Abstract

This article reports and analyzes a case of postoperative tuberculosis infection in an 80-year-old female after total hip arthroplasty, which was misdiagnosed and mistreated due to imaging findings resembling a pseudo-bursa cyst. The patient had a history of right femoral neck fracture, underwent right total hip arthroplasty 4 years ago, and developed a lump on the posterior side of the right thigh 1 year ago. Initial MRI at another hospital diagnosed it as a pseudo-bursa cyst and underwent excision surgery, but recurred 2 months later. Upon admission, repeated fluid aspiration, biochemical analysis of the fluid (showing high protein, high specific gravity, and positive Rivalta test), PPD, and T-SPOT.TB tests all indicated active tuberculosis infection. Cheese-like necrosis and granuloma formation were found during surgery, confirming postoperative tuberculosis infection. The patient underwent local debridement surgery combined with 9 months of standard HRZE anti-tuberculosis treatment (isoniazid, rifampicin, pyrazinamide, and ethambutol). Follow-up at 9 months showed the lump had disappeared, inflammatory markers returned to normal, and the prosthetic joint remained stable with improved joint function. This case highlights the challenge of tuberculosis infection being masked by common postoperative complications, emphasizing the importance of multidimensional examination and comprehensive diagnosis of diseased tissues to reduce misdiagnosis rates, improve treatment success rates, and enhance patient quality of life.

摘要

本文报道并分析了一例80岁女性全髋关节置换术后发生结核感染的病例,该病例因影像学表现类似假性滑液囊肿而被误诊误治。患者有右股骨颈骨折病史,4年前接受了右全髋关节置换术,1年前右大腿后侧出现肿块。外院初次MRI诊断为假性滑液囊肿并进行了切除手术,但2个月后复发。入院后,反复抽液、对液体进行生化分析(显示高蛋白、高比重、利凡他试验阳性)、PPD及T-SPOT.TB检测均提示活动性结核感染。手术中发现干酪样坏死及肉芽肿形成,确诊为术后结核感染。患者接受了局部清创手术并联合9个月的标准HRZE抗结核治疗(异烟肼、利福平、吡嗪酰胺和乙胺丁醇)。9个月的随访显示肿块消失,炎症指标恢复正常,假体关节保持稳定,关节功能改善。该病例凸显了结核感染被常见术后并发症掩盖的挑战,强调了对病变组织进行多维度检查和综合诊断以降低误诊率、提高治疗成功率及改善患者生活质量的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ef5/12148853/51637cee784f/fsurg-12-1612055-g001.jpg

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