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减肥手术的安全路径:术前患者的心理健康障碍

A safe path to bariatric surgery: Mental health disorders in pre-operative patients.

作者信息

El Alam Andrew, Fleifel Mohamad, Baba Hicham, Bayda Souha, Nassani Bertha Maria, Azar Jocelyne, Monier Arnaud

机构信息

Endocrinology and Metabolism Division, Lebanese American University, Beirut, Lebanon.

Endocrinology and Metabolism Division, American University of Beirut Medical Center, Beirut, Lebanon.

出版信息

Compr Psychoneuroendocrinol. 2025 May 15;23:100300. doi: 10.1016/j.cpnec.2025.100300. eCollection 2025 Aug.

Abstract

BACKGROUND

Obesity is one of the most significant global health concerns. As per the World Health Organization (WHO), obesity currently affects nearly 1.9 billion individuals around the world. Patients suffering from such a metabolic disease exhibit multiple medical conjoint medical conditions, and are predisposed to future high-morbidity and mortality complications. In addition, such patients might suffer from psychiatric compromises, at any time during their lives, that might have contributed to obesity. For many of these patients, bariatric surgery remains one of the leading methodologies in facilitating weight loss.

AIM

To study the prevalence of selected mental health disorders history, including depression, childhood trauma, and eating disorders, plus abnormal eating behaviors in patients with obesity undergoing pre-bariatric surgery evaluation. In addition, we intended to find any inter-associations between different mental health disorders and demographics in such patients.

METHODS

In this cross-sectional study, conducted at the Nutrition and Obesity Department at Louis Pasteur Hospital, France, we enrolled 234 patients with obesity undertaking pre-bariatric surgery evaluation.

RESULTS

Around 31.2 % of participants had a history of depression, with 46.5 % receiving treatment. Childhood trauma was identified in 22.6 % of patients, and 12.8 % exhibited eating disorders, subclassified into binge eating disorder (6.4 %), bulimia (3.2 %), and night eating syndrome (3.4 %). Abnormal eating behaviors was also prominent in such patients, with 66.2 % engaging in activities such as snacking, hyperphagia, emotional eating, and compulsive eating. Sociodemographic associations showed that females were more likely to be diagnosed with depression, binge eating disorder, and compulsive eating, while males were more prone to hyperphagia. Childhood trauma was significantly associated with depression, binge eating disorder, bulimia, and abnormal eating behaviors. Multinomial logistic regression analysis revealed various predictors for depression, eating disorders, and abnormal eating behaviors across different categories. Notably, depression was associated with unemployment, trauma, and compulsions. Binge eating disorder showed significant associations with trauma and the female sex, while bulimia was notably associated with trauma. Night eating syndrome was inversely related to marriage status. Subgroup analysis further highlighted associations between depression, eating disorders, and abnormal eating behaviors in specific demographic groups.

CONCLUSION

There is a complex link between mental health disorders and eating patterns in individuals with obesity undergoing pre-bariatric surgery evaluation. Understanding this association is important for developing comprehensive preoperative care strategies that address both physical and mental health aspects in the management of obesity.

摘要

背景

肥胖是全球最重大的健康问题之一。根据世界卫生组织(WHO)的数据,目前全球近19亿人受到肥胖影响。患有这种代谢性疾病的患者存在多种合并症,且未来易发生高发病率和高死亡率的并发症。此外,这类患者在其生命中的任何时候都可能存在精神方面的问题,而这可能导致了肥胖。对于许多此类患者而言,减肥手术仍是促进体重减轻的主要方法之一。

目的

研究接受减肥手术前评估的肥胖患者中特定心理健康障碍史(包括抑郁症、童年创伤和饮食失调)以及异常饮食行为的患病率。此外,我们旨在找出此类患者中不同心理健康障碍与人口统计学特征之间的任何相互关联。

方法

在法国路易·巴斯德医院营养与肥胖科进行的这项横断面研究中,我们纳入了234名接受减肥手术前评估的肥胖患者。

结果

约31.2%的参与者有抑郁症病史,其中46.5%正在接受治疗。22.6%的患者存在童年创伤,12.8%的患者表现出饮食失调,细分为暴饮暴食症(6.4%)、贪食症(3.2%)和夜间饮食综合征(3.4%)。此类患者中异常饮食行为也很突出,66.2%的患者有吃零食、暴饮暴食、情绪化进食和强迫性进食等行为。社会人口统计学关联显示,女性更易被诊断出患有抑郁症、暴饮暴食症和强迫性进食,而男性更容易暴饮暴食。童年创伤与抑郁症、暴饮暴食症、贪食症和异常饮食行为显著相关。多项逻辑回归分析揭示了不同类别中抑郁症、饮食失调和异常饮食行为的各种预测因素。值得注意的是,抑郁症与失业、创伤和强迫行为有关。暴饮暴食症与创伤和女性性别显著相关,而贪食症与创伤显著相关。夜间饮食综合征与婚姻状况呈负相关。亚组分析进一步突出了特定人口统计学群体中抑郁症、饮食失调和异常饮食行为之间的关联。

结论

在接受减肥手术前评估的肥胖个体中,心理健康障碍与饮食模式之间存在复杂的联系。了解这种关联对于制定全面的术前护理策略很重要,该策略应在肥胖管理中兼顾身心健康方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b0a5/12149645/92936878722b/gr1.jpg

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